Interpretation of Carbon-13 NMR Spectra

Abstract

Basic Principles: History of Carbon-13 NMR, Relaxation and Nuclear Overhauser Effect, Instrumental Requirements The Spectral Parameters: The Chemical Shift, Spin- Spin Coupling Experimental Techniques for Spectral Assignment: Summary of Methods, Proton Decoupling Techniques, Polarization Transfer and Related Experiments, Selective Excitation, Two- Dimensional Experiments, Carbon-Carbon Connectivity Experiments, Lanthanide Shift Reagents, Chemical Shift Comparison, Isotope Effect, Solid State 13 C NMR Nuclear Spin Relaxation: Correlation and Spectral Density Function, Dipole-Dipole Relaxation, Other Relaxation Mechanisms, Anisotropic Rotational Diffusion, Experimental Techniques for the Measurement of T 1, and the Nuclear Overhauser Effect (NOE), Temperature and Concentration Dependence of the Rotational Correlation Time, Relative Contributions from Individual Relaxation Mechanisms Applications: Structure Elucidation of Organic Molecules, Dynamic Processes, Conformational Analysis, 2-D Techniques for the Elucidation of Exchange, Rotamer Equilibria, Macromolecules, Solid-State 13 C NMR Applications, Mechanistic Studies, Spin- Lattice Relaxation and Nuclear Overhauser Studies, Quantitative, Analysis.