Leaderboards/Telomeres, Telomerase, and Senescence

Telomeres, Telomerase, and Senescence

Last updated June 1, 2026

Rising Stars

New and hot

Rising Stars Researchers

1
George A. Garinis
University of Crete
85
2
Umberto Galderisi
University of Campania "Luigi Vanvitelli"
74
3
Roderick J. O’Sullivan
UPMC Health System
74
4
Marco Demaria
University Medical Center Groningen
63
5
Aungkura Supokawej
Mahidol University
52
6
Jungang Xie
Tongji Hospital
33
7
Daniela Monti
University of Florence
25
8
Kevin N. Hascup
Southern Illinois University School of Medicine
23
9
Johnny Huard
Steadman Philippon Research Institute
22
10
Sinem E. Sahingur
University of Pennsylvania
20

Rising Stars Papers

1
IGFBP7 is a key component of the senescence-associated secretory phenotype (SASP) that induces senescence in healthy cells by modulating the insulin, IGF, and activin A pathways
Cell Communication and Signaling|2024
30 cit.
2
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD
Journal of Advanced Research|2024
28 cit.
3
Quercetin induces senolysis of doxorubicin-induced senescent fibroblasts by reducing autophagy, preventing their pro-tumour effect on osteosarcoma cells
Mechanisms of Ageing and Development|2024
24 cit.
4
Deregulated DNA ADP-ribosylation impairs telomere replication
Nature Structural & Molecular Biology|2024
22 cit.
5
Converting cell death into senescence by PARP1 inhibition improves recovery from acute oxidative injury
Nature Aging|2024
22 cit.
6
Senolytic intervention improves cognition, metabolism, and adiposity in female APPNL−F/NL−F mice
GeroScience|2024
22 cit.
7
IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors
Cell Communication and Signaling|2024
20 cit.
8
HIRA protects telomeres against R-loop-induced instability in ALT cancer cells
Cell Reports|2024
20 cit.
9
Enhanced potent immunosuppression of intracellular adipose tissue-derived stem cell extract by priming with three-dimensional spheroid formation
Scientific Reports|2024
19 cit.
10
Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence
Nature Communications|2024
19 cit.

Emerging Leaders

Gaining momentum

Emerging Leaders Researchers

1
Xiaojing Liu
Sichuan University
99
2
Oscar Flórez-Vargas
National Cancer Institute
99
3
J. P. W. Joung
Seoul National University
99
4
Alexander P. Sobinoff
Children's Medical Research Institute
99
5
Yu‐Wei Ling
Xijing Hospital
99
6
Sahil A Mapkar
New York University
99
7
Mélina Vaurs
de Duve Institute
99
8
Takumi Mikawa
Kyoto University
83
9
Eszter Bajtai
Semmelweis University
75
10
Florence Couteau
Hôpital Maisonneuve-Rosemont
75

Emerging Leaders Papers

1
Therapy-induced senescence is a transient drug resistance mechanism in breast cancer
Molecular Cancer|2025
29 cit.
2
Genetic regulation of TERT splicing affects cancer risk by altering cellular longevity and replicative potential
Nature Communications|2025
12 cit.
3
Cell enlargement modulated by GATA4 and YAP instructs the senescence-associated secretory phenotype
Nature Communications|2025
11 cit.
4
Mechanical rejuvenation of senescent stem cells and aged bone via chromatin remodeling
Nature Communications|2026
10 cit.
5
TRF1 relies on fork reversal to prevent fragility at human telomeres
Nature Communications|2025
7 cit.
6
Nuclear morphometrics coupled with machine learning identifies dynamic states of senescence across age
Nature Communications|2025
5 cit.
7
Diabetes reshapes pancreatic cancer-associated endothelial niche by accelerating senescence
Nature Communications|2025
5 cit.
8
<i>R</i>-2-hydroxyglutarate-mediated inhibition of KDM4A compromises telomere integrity
Nucleic Acids Research|2025
4 cit.
9
NONO, SFPQ, and PSPC1 promote telomerase recruitment to the telomere
Nature Communications|2025
3 cit.
10
Abrogation of aberrant glycolytic interactions eliminates senescent cells and alleviates aging-related dysfunctions
Signal Transduction and Targeted Therapy|2025
3 cit.

All-Time Leaders

The canon

All-Time Leaders Researchers

1
James L. Kirkland
Mayo Clinic in Florida
94
2
Jesús Gil
MRC London Institute of Medical Sciences
84
3
Birgit Schilling
Buck Institute for Research on Aging
82
4
Nathan K. LeBrasseur
Mayo Clinic
82
5
Fabrizio d’Adda di Fagagna
IFOM
79
6
Thea D. Tlsty
University of California, San Francisco
75
7
Valery Krizhanovsky
Weizmann Institute of Science
75
8
Scott W. Lowe
Memorial Sloan Kettering Cancer Center
72
9
Ronald A. DePinho
The University of Texas MD Anderson Cancer Center
72
10
Paul D. Robbins
University of Minnesota
71

All-Time Leaders Papers

1
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
Aging Cell|2015
2.4k cit.
2
Genetics and biology of pancreatic ductal adenocarcinoma
Genes & Development|2006
1.6k cit.
3
Cellular senescence mediates fibrotic pulmonary disease
Nature Communications|2017
1.5k cit.
4
A proteomic atlas of senescence-associated secretomes for aging biomarker development
PLoS Biology|2020
1.3k cit.
5
Malignant glioma: genetics and biology of a grave matter
Genes & Development|2001
1.2k cit.
6
Senescence and aging: Causes, consequences, and therapeutic avenues
The Journal of Cell Biology|2017
1.2k cit.
7
Senescence and the SASP: many therapeutic avenues
Genes & Development|2020
1.1k cit.
8
Activated Kras and <i>Ink4a/Arf</i> deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
Genes & Development|2003
1k cit.
9
Cellular senescence and senolytics: the path to the clinic
Nature Medicine|2022
1k cit.
10
Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity
Genes & Development|2011
990 cit.

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