Leaderboards/Telomeres, Telomerase, and Senescence

Telomeres, Telomerase, and Senescence

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Victoria Moiseeva
Universitat Pompeu Fabra
2
Julia Majewska
Weizmann Institute of Science
3
Léa Montégut
Icahn School of Medicine at Mount Sinai
4
Scott Haston
University College London
5
Qing Zeng
Southern Medical University
6
Indra Heckenbach
University of Copenhagen
7
Ines Sturmlechner
Mayo Clinic
8
Luis I. Prieto
Mayo Clinic in Arizona
9
Goro Katsuumi
Juntendo University
10
Jinghui Lei
Capital Medical University

Papers

1
Publication in Molecular Cancer (2024) [159 citations, W4397044051]
Molecular Cancer|2024
159 cit.
2
Lipids and lipid metabolism in cellular senescence: Emerging targets for age-related diseases
Ageing Research Reviews|2024
152 cit.
3
SGLT2 inhibition eliminates senescent cells and alleviates pathological aging
Nature Aging|2024
126 cit.
4
p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells
Nature Cell Biology|2024
91 cit.
5
Publication in Cell (2025) [53 citations, W4411276971]
Cell|2025
53 cit.
6
Publication in Molecular Cancer (2024) [24 citations, W4402321108]
Molecular Cancer|2024
24 cit.
7
Deep learning assessment of senescence-associated nuclear morphologies in mammary tissue from healthy female donors to predict future risk of breast cancer: a retrospective cohort study
The Lancet Digital Health|2024
16 cit.
8
Publication in OncoImmunology (2024) [16 citations, W4403190877]
OncoImmunology|2024
16 cit.
9
Publication in Nature Aging (2025) [16 citations, W4413138091]
Nature Aging|2025
16 cit.
10
Antigen specificity shapes distinct aging trajectories of memory CD8⁺ T cells
Nature Communications|2025
15 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Anoop M. Nambiar
The University of Texas at San Antonio Health Science Center
2
Shahrukh Hashmi
Abu Dhabi Health Services
3
Miranda E. Orr
Washington University in St. Louis
4
Noelia Alcázar
Institute for Research in Biomedicine
5
Satotaka Omori
Coherus BioSciences (United States)
6
Teh-Wei Wang
The University of Tokyo
7
Takehiro Yamanaka
The University of Tokyo
8
Si Wang
First Affiliated Hospital of Wannan Medical College
9
Gonçalo Castelo‐Branco
Karolinska Institutet
10
Thomas Champion
Hospital Central Militar

Papers

1
Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability
EBioMedicine|2023
256 cit.
2
Senolytic therapy in mild Alzheimer’s disease: a phase 1 feasibility trial
Nature Medicine|2023
247 cit.
3
Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag
Nature Biotechnology|2022
133 cit.
4
Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology
Cell|2024
105 cit.
5
Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility
Neuron|2022
100 cit.
6
Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis
Developmental Cell|2022
82 cit.
7
Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling
Acta Neuropathologica Communications|2022
72 cit.
8
Spatial and temporal heterogeneity in the lineage progression of fine oligodendrocyte subtypes
BMC Biology|2022
60 cit.
9
Aging hallmarks of the primate ovary revealed by spatiotemporal transcriptomics
Protein & Cell|2023
57 cit.
10
A single-nucleus transcriptomic atlas of primate testicular aging reveals exhaustion of the spermatogonial stem cell reservoir and loss of Sertoli cell homeostasis
Protein & Cell|2022
53 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Titia de Lange
Rockefeller University
2
Judith Campisi
Buck Institute for Research on Aging
3
Jerry W. Shay
Southwestern Medical Center
4
Marı́a A. Blasco
Spanish National Cancer Research Centre
5
Carol W. Greider
University of California, Santa Cruz
6
Elizabeth H. Blackburn
Rutgers, The State University of New Jersey
7
Thomas R. Cech
Howard Hughes Medical Institute
8
James L. Kirkland
Cedars-Sinai Medical Center
9
Ronald A. DePinho
The University of Texas MD Anderson Cancer Center
10
Roger R. Reddel
Cancer Clinic

Papers

1
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer
Science|1994
7.1k cit.
2
Telomeres shorten during ageing of human fibroblasts
Nature|1990
5.7k cit.
3
Identification of a specific telomere terminal transferase activity in tetrahymena extracts
Cell|1985
3.4k cit.
4
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
Aging Cell|2015
2.4k cit.
5
Mammalian Telomeres End in a Large Duplex Loop
Cell|1999
2.4k cit.
6
Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena
Cell|1982
2.3k cit.
7
Telomerase Catalytic Subunit Homologs from Fission Yeast and Human
Science|1997
2.3k cit.
8
Senolytics improve physical function and increase lifespan in old age
Nature Medicine|2018
2.2k cit.
9
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
Nature Cell Biology|2009
2.2k cit.
10
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
Cell|1997
2.1k cit.

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