Leaderboards/Synthesis and Biological Activity

Synthesis and Biological Activity

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Aysha Fatima
Jiwaji University
2
Andrew T. McNutt
University of Pittsburgh
3
Bulti Bakchi
National Institute of Pharmaceutical Education and Research - Ahmedabad
4
Xun-Cai Yang
Southwest University
5
Yassine Laamari
Cadi Ayyad University
6
Mohammed Er-rajy
Sidi Mohamed Ben Abdellah University
7
K.J. Rajimon
Sacred Heart College
8
Ossama Daouı
Sidi Mohamed Ben Abdellah University
9
Anand Kumar Yadav
Tribhuvan University
10
Ezaddine Irrou
Université Ibn Zohr

Papers

1
GNINA 1.3: the next increment in molecular docking with deep learning
Journal of Cheminformatics|2025
105 cit.
2
Anticancer mechanism of coumarin-based derivatives
European Journal of Medicinal Chemistry|2024
88 cit.
3
Publication in Journal of Molecular Structure (2024) [36 citations, W4400083030]
Journal of Molecular Structure|2024
36 cit.
4
Publication in Journal of Molecular Structure (2024) [33 citations, W4402513289]
Journal of Molecular Structure|2024
33 cit.
5
Synthesis, characterization, anticancer activity, molecular docking and DFT calculation of 3-acetylcoumarin thiosemicarbazones and Schiff’s bases
Results in Chemistry|2024
23 cit.
6
Exploring the structure and dynamics of a fluorescent schiff base (1E,1′E)-1,1′-(1,4-phenylene) bis(N-(4-chlorophenyl) methamine: Synthesis, spectroscopic analysis, thermal, electronic and crystallographic study with biological applications
Journal of Molecular Structure|2024
20 cit.
7
Publication in Frontiers in Chemistry (2025) [20 citations, W4408206958]
Frontiers in Chemistry|2025
20 cit.
8
An in-depth study of the synthesis, electronic framework, and pharmacological profiling of 1-(anthracen-9-yl)-N-(4-nitrophenyl) methanimine: In vitro and in silico investigations on molecular docking, dynamics simulation, BSA/DNA binding and toxicity studies
Chemical Physics Impact|2024
19 cit.
9
Publication in Journal of the Indian Chemical Society (2025) [18 citations, W4407836327]
Journal of the Indian Chemical Society|2025
18 cit.
10
Publication in Journal of Molecular Structure (2024) [7 citations, W4401005032]
Journal of Molecular Structure|2024
7 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Bahaa G. M. Youssif
Assiut University
2
Aly Abdou
Sohag University
3
Hitler Louis
Federal University of Petroleum Resource Effurun
4
Khalid Karrouchi
Mohammed V University
5
Samir Chtita
MRC Laboratory of Molecular Biology
6
Hayat Ullah
University of Okara
7
N. Elangovan
Saveetha University
8
Eman S. Nossier
Al-Azhar University
9
Jamal Saeh
AstraZeneca (Brazil)
10
Yusuf Sert
Yozgat Bozok Üniversitesi

Papers

1
Quantum computational, spectroscopic investigations on N-(2-((2-chloro-4,5-dicyanophenyl)amino)ethyl)-4-methylbenzenesulfonamide by DFT/TD-DFT with different solvents, molecular docking and drug-likeness researches
Colloids and Surfaces A Physicochemical and Engineering Aspects|2022
387 cit.
2
New Heterocyclic Compound as Carbon Steel Corrosion Inhibitor in 1 M H<sub>2</sub>SO<sub>4</sub>, High Efficiency at Low Concentration: Experimental and Theoretical Studies
Journal of Adhesion Science and Technology|2022
172 cit.
3
Fabrication, structural elucidation, theoretical, TD-DFT, vibrational calculation and molecular docking studies of some novel adenine imine chelates for biomedical applications
Journal of Molecular Liquids|2022
95 cit.
4
Modeling of Ca12O12, Mg12O12, and Al12N12 nanostructured materials as sensors for phosgene (Cl2CO)
Materials Today Communications|2022
92 cit.
5
Fe(III), Ni(II), and Cu(II)-moxifloxacin-tri-substituted imidazole mixed ligand complexes: Synthesis, structural, DFT, biological, and protein-binding analysis
Inorganic Chemistry Communications|2023
85 cit.
6
Design of novel benzimidazole derivatives as potential α-amylase inhibitors using QSAR, pharmacokinetics, molecular docking, and molecular dynamics simulation studies
Journal of Molecular Modeling|2022
81 cit.
7
Synthesis, characterization, DFT, biological activity evaluation, and molecular docking analysis of new 8-[(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1,3-disulfonic acid based complexes
Journal of Molecular Structure|2023
79 cit.
8
RETRACTED: Probing the Reactions of Thiourea (CH<sub>4</sub>N<sub>2</sub>S) with Metals (X = Au, Hf, Hg, Ir, Os, W, Pt, and Re) Anchored on Fullerene Surfaces (C<sub>59</sub>X)
ACS Omega|2022
78 cit.
9
Computational Investigation on Structural and Reactive Sites (HOMO-LUMO, MEP, NBO, NPA, ELF, LOL, RDG) Identification, Pharmacokinetic (ADME) Properties and Molecular Docking Investigation of (E)-4-((4-chlorobenzylidene) amino) Benzene Sulfonamide Compound
Analytical Chemistry Letters|2022
77 cit.
10
Combined computational approaches for developing new anti-Alzheimer drug candidates: 3D-QSAR, molecular docking and molecular dynamics studies of liquiritigenin derivatives
Heliyon|2022
74 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Hai‐Liang Zhu
Nanjing Drum Tower Hospital
2
S. Muthu
Anna University, Chennai
3
Abbas Shafiee
Translational Research Institute
4
Khalid Mohammed Khan
Pakistan Agricultural Research Council
5
Erik De Clercq
Rega Institute for Medical Research
6
Ernest Hamel
National Institutes of Health
7
Cheng‐He Zhou
Southwest University
8
Kuo‐Hsiung Lee
University of North Carolina at Chapel Hill
9
Kanchugarakoppal S. Rangappa
University of Mysore
10
Roman Lesyk
Danylo Halytsky Lviv National Medical University

Papers

1
Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds
Journal of Virological Methods|1988
1.6k cit.
2
A novel selective broad-spectrum anti-DNA virus agent
Nature|1986
764 cit.
3
Comparative Efficacy of Antiherpes Drugs against Different Strains of Herpes Simplex Virus
The Journal of Infectious Diseases|1980
604 cit.
4
Synthesis, antibacterial, antifungal and anti-HIV activities of Schiff and Mannich bases derived from isatin derivatives and N-[4-(4′-chlorophenyl)thiazol-2-yl] thiosemicarbazide
European Journal of Pharmaceutical Sciences|1999
581 cit.
5
Inhibition of T-tropic HIV Strains by Selective Antagonization of the Chemokine Receptor CXCR4
The Journal of Experimental Medicine|1997
556 cit.
6
Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus
Antimicrobial Agents and Chemotherapy|1988
542 cit.
7
Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines
Antiviral Research|1987
513 cit.
8
Activities of the Microtubule-stabilizing Agents Epothilones A and B with Purified Tubulin and in Cells Resistant to Paclitaxel (Taxol®)
Journal of Biological Chemistry|1997
512 cit.
9
(E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.
Proceedings of the National Academy of Sciences|1979
482 cit.
10
Heavy metals in surface sediments of the Jialu River, China: Their relations to environmental factors
Journal of Hazardous Materials|2014
478 cit.

Reagents for Synthesis and Biological Activity

Citation-validated products used in this field

🔥 Trending

Gaining adoption fast

⭐ Top Rated

Best all-around

Cell Signaling TechnologyEvidence 64

GIT2 Antibody

#6953$317
View Evidence →
Cell Signaling TechnologyEvidence 66

HSP90 (C45G5) Rabbit Monoclonal Antibody (SignalFlex™ mFluor™ Violet 510 Conjugate)

#90303$458
View Evidence →
Cell Signaling TechnologyEvidence 61

Langerin (F8L8I) Rabbit Monoclonal Antibody

#36418$178,415
View Evidence →

🌟 All-Time

Most validated

Cell Signaling TechnologyEvidence 66

Mcl-1 (D2W9E) Rabbit Monoclonal Antibody

Cited in 5 papers
#94296$173,351
View Evidence →
Cell Signaling Technology

Phospho-cdc2 (Thr161) Antibody

#9114$362
View Evidence →
Cell Signaling TechnologyEvidence 66

EpCAM (VU1D9) Mouse Monoclonal Antibody (Pacific Blue™ Conjugate)

#9032$465
View Evidence →