Leaderboards/siRNA

siRNA

Last updated May 19, 2026

Rising Stars

New and hot

Rising Stars Researchers

1
Yan Zhuo
Nanchang University
358 cit.
2
Yu Zhao
Harbin Medical University
243 cit.
3
Namit Chaudhary
Carnegie Mellon University
223 cit.
4
Fan Zhang
Wenzhou Medical University
198 cit.
5
Meng Guan
Wuhan National Laboratory for Optoelectronics
168 cit.
6
Kausik K. Ray
Imperial College London
168 cit.
7
Miao Xie
Shanghai Jiao Tong University
150 cit.
8
Graham Arrick
Massachusetts Institute of Technology
150 cit.
9
Thi My Hue Huynh
National Tsing Hua University
138 cit.
10
Amogh Vaidya
The University of Texas Southwestern Medical Center
132 cit.

Rising Stars Papers

1
Direct cytosolic delivery of siRNA via cell membrane fusion using cholesterol-enriched exosomes
Nature Nanotechnology|2024
142 cit.
2
Polymer-locking fusogenic liposomes for glioblastoma-targeted siRNA delivery and CRISPR–Cas gene editing
Nature Nanotechnology|2024
96 cit.
3
Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d
Nature Biomedical Engineering|2024
88 cit.
4
A dynamically phase-adaptive regulating hydrogel promotes ultrafast anti-fibrotic wound healing
Nature Communications|2025
98 cit.
5
Regulating copper homeostasis of tumor cells to promote cuproptosis for enhancing breast cancer immunotherapy
Nature Communications|2024
83 cit.
6
Durability and efficacy of solbinsiran, a GalNAc-conjugated siRNA targeting ANGPTL3, in adults with mixed dyslipidaemia (PROLONG-ANG3): a double-blind, randomised, placebo-controlled, phase 2 trial
The Lancet|2025
55 cit.
7
Membrane Fusion‐Mediated Loading of Therapeutic siRNA into Exosome for Tissue‐Specific Application
Advanced Materials|2024
74 cit.
8
Cephalopod-inspired jetting devices for gastrointestinal drug delivery
Nature|2024
49 cit.
9
Reprogramming Immunodeficiency in Lung Metastases via PD-L1 siRNA Delivery and Antigen Capture of Nanosponge-Mediated Dendritic Cell Modulation
ACS Nano|2025
68 cit.
10
Expanding RNAi to Kidneys, Lungs, and Spleen via Selective ORgan Targeting (SORT) siRNA Lipid Nanoparticles
Advanced Materials|2024
65 cit.

Rising Stars Reagents

Coming soon

Emerging Leaders

Gaining momentum

Emerging Leaders Researchers

1
Martin A. Maier
Alnylam Pharmaceuticals (United States)
270 cit.
2
Jun Yu
Chinese University of Hong Kong
161 cit.
3
Heiko Hermeking
German Cancer Research Center
147 cit.
4
Daniel G. Anderson
Boston Children's Hospital
143 cit.
5
Arthur A. Levin
Fleet Science Center
125 cit.
6
Zihua Wang
Fujian Medical University
105 cit.
7
Cheng‐Chao Ruan
Shanghai Medical College of Fudan University
102 cit.
8
Thomas H. Sharp
Leiden University Medical Center
100 cit.
9
Huili Zhang
Shanghai Ninth People's Hospital
93 cit.
10
Feng Zhang
Nanjing University of Chinese Medicine
93 cit.

Emerging Leaders Papers

1
RNA interference in the era of nucleic acid therapeutics
Nature Biotechnology|2024
180 cit.
2
Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis
Cell Death and Differentiation|2023
176 cit.
3
Recent advances in nanoparticulate RNA delivery systems
Proceedings of the National Academy of Sciences|2024
95 cit.
4
Targeted tissue delivery of RNA therapeutics using antibody–oligonucleotide conjugates (AOCs)
Nucleic Acids Research|2023
125 cit.
5
METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy
Cell Reports Medicine|2023
140 cit.
6
Biomimetic Nanovesicles as a Dual Gene Delivery System for the Synergistic Gene Therapy of Alzheimer’s Disease
ACS Nano|2024
105 cit.
7
ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice
Nature Communications|2024
102 cit.
8
Liquid crystalline inverted lipid phases encapsulating siRNA enhance lipid nanoparticle mediated transfection
Nature Communications|2024
100 cit.
9
Hydrogen sulfide protects cardiomyocytes from doxorubicin-induced ferroptosis through the SLC7A11/GSH/GPx4 pathway by Keap1 S-sulfhydration and Nrf2 activation
Redox Biology|2024
186 cit.
10
Canonical Wnt signaling promotes HSC glycolysis and liver fibrosis through an LDH-A/HIF-1α transcriptional complex
Hepatology|2023
139 cit.

Emerging Leaders Reagents

Coming soon

All-Time Leaders

The canon

All-Time Leaders Researchers

1
Thomas Tuschl
Max Planck Society
41.8k cit.
2
Phillip D. Zamore
Unknown
14.5k cit.
3
Matthew J. A. Wood
University of Oxford
14.3k cit.
4
Reuven Agami
Genesis Foundation
12.9k cit.
5
Chuan He
University of Chicago
12.3k cit.
6
David P. Bartel
Massachusetts Institute of Technology
11.4k cit.
7
Ramin Shiekhattar
The Wistar Institute
10.9k cit.
8
Keming Zhu
Second Military Medical University
10.7k cit.
9
Patrick X. Zhao
Unknown
10.2k cit.
10
James C. Carrington
Oregon State University
10k cit.

All-Time Leaders Papers

1
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
Nature|2001
9.4k cit.
2
Real-time quantification of microRNAs by stem-loop RT-PCR
Nucleic Acids Research|2005
5k cit.
3
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Nature Biotechnology|2011
4.8k cit.
4
A System for Stable Expression of Short Interfering RNAs in Mammalian Cells
Science|2002
4.3k cit.
5
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
Nature Chemical Biology|2011
4.1k cit.
6
MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing
Molecular Cell|2007
3.8k cit.
7
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
Cellular Physiology and Biochemistry|2017
10.7k cit.
8
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
Proceedings of the National Academy of Sciences|2009
2.9k cit.
9
Asymmetry in the Assembly of the RNAi Enzyme Complex
Cell|2003
2.8k cit.
10
The polycomb group protein EZH2 is involved in progression of prostate cancer
Nature|2002
2.7k cit.

All-Time Leaders Reagents

Coming soon

Indexing siRNA Reagents

Citation data for reagents in this field is currently compiling.