Leaderboards/Receptor Mechanisms and Signaling

Receptor Mechanisms and Signaling

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Kazumasa Kanemaru
Wellcome/MRC Cambridge Stem Cell Institute
2
Gáspár Pándy‐Szekeres
University of Copenhagen
3
Cédric Bouysset
Recursion (United States)
4
Katheryn B. Lefton
Washington University in St. Louis
5
Emi Ling
Broad Institute
6
Kuei-Pin Huang
Monell Chemical Senses Center
7
Qianqian Xin
Zhejiang Lab
8
Makaía M. Papasergi-Scott
Stanford University
9
Casper A. Goverde
SIB Swiss Institute of Bioinformatics
10
Huijeong Jeong
University of California, San Francisco

Papers

1
Publication in Nature (2024) [144 citations, W4392504626]
Nature|2024
144 cit.
2
Dissociable hindbrain GLP1R circuits for satiety and aversion
Nature|2024
141 cit.
3
Publication in Nature (2024) [125 citations, W4392747552]
Nature|2024
125 cit.
4
Publication in Nature (2024) [124 citations, W4399830285]
Nature|2024
124 cit.
5
Memory erasure by dopamine-gated retrospective learning
bioRxiv (Cold Spring Harbor Laboratory)|2026
1 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Yuanyuan Zhang
Westlake University
2
Denise Wootten
Monash University
3
E. Marie Parsons
Boston University
4
Ron O. Dror
Stanford University
5
Lin Tian
Shriners Hospitals for Children - Northern California
6
Ryan Hibbs
University of California San Diego
7
Ilana B. Witten
Princeton University
8
Jounhong Ryan Cho
California Institute of Technology
9
Jordi Bonaventura
Bellvitge University Hospital
10
Aaron A. Thompson
Janssen (United States)

Papers

1
Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state
Nature Neuroscience|2022
114 cit.
2
Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities
Nature Communications|2022
95 cit.
3
How accurately can one predict drug binding modes using AlphaFold models?
eLife|2023
94 cit.
4
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation
Nature Communications|2022
84 cit.
5
Structural mechanism of muscle nicotinic receptor desensitization and block by curare
Nature Structural & Molecular Biology|2022
83 cit.
6
Structural mechanisms of GABAA receptor autoimmune encephalitis
Cell|2022
73 cit.
7
Structural insights into opposing actions of neurosteroids on GABAA receptors
Nature Communications|2023
73 cit.
8
A brain-wide map of neural activity during complex behaviour
Nature|2025
72 cit.
9
How accurately can one predict drug binding modes using AlphaFold models?
eLife|2023
61 cit.
10
Sensory specializations drive octopus and squid behaviour
Nature|2023
60 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Robert J. Lefkowitz
Howard Hughes Medical Institute
2
Brian K. Kobilka
Stanford University
3
Marc G. Caron
Duke University
4
Solomon H. Snyder
Johns Hopkins University
5
Bryan L. Roth
University of North Carolina at Chapel Hill
6
Raymond C. Stevens
University of Miami
7
Paul Greengard
Rockefeller University
8
Michel Bouvier
Institute for Research in Immunology and Cancer
9
Eric J. Nestler
Allen Institute for Brain Science
10
Martin J. Lohse
University of Würzburg

Papers

1
Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.
Proceedings of the National Academy of Sciences|1990
3.3k cit.
2
High-Resolution Crystal Structure of an Engineered Human β <sub>2</sub> -Adrenergic G Protein–Coupled Receptor
Science|2007
3.3k cit.
3
Crystal structure of the β2 adrenergic receptor–Gs protein complex
Nature|2011
3.1k cit.
4
Opiate Receptor: Demonstration in Nervous Tissue
Science|1973
2.4k cit.
5
Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase
Nature|1991
2.4k cit.
6
Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions
Cell|2007
2.3k cit.
7
Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs
Science|1976
2.2k cit.
8
Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress
Science|2006
2.1k cit.
9
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand
Proceedings of the National Academy of Sciences|2007
2.1k cit.
10
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
Nature|2007
1.9k cit.

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