Leaderboards/Pulmonary Hypertension Research and Treatments

Pulmonary Hypertension Research and Treatments

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Serena Lucotti
Cornell University
2
Ruaa Al‐Qazazi
Queen's University
3
Sarah‐Eve Lemay
SNC-Lavalin (Canada)
4
Lloyd D. Harvey
University of Pittsburgh
5
Fenghua Bian
Cincinnati Children's Hospital Medical Center
6
Felix A. Trogisch
University of Mannheim
7
Paul M. Hendriks
Erasmus University Rotterdam
8
Julien Grynblat
Hôpital Necker-Enfants Malades
9
Yuetan Chu
King Abdullah University of Science and Technology
10
Zhiheng Sun
Nanjing University

Papers

1
Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9
Science Translational Medicine|2024
56 cit.
2
Publication in Cell (2025) [49 citations, W4407369197]
Cell|2025
49 cit.
3
Lactate facilitated mitochondrial fission-derived ROS to promote pulmonary fibrosis via ERK/DRP-1 signaling
Journal of Translational Medicine|2024
45 cit.
4
Publication in The FASEB Journal (2024) [30 citations, W4390918855]
The FASEB Journal|2024
30 cit.
5
Lactate activates ER stress to promote alveolar epithelial cells apoptosis in pulmonary fibrosis
Respiratory Research|2024
29 cit.
6
Publication in European Respiratory Journal (2024) [24 citations, W4393033898]
European Respiratory Journal|2024
24 cit.
7
Exploring Integrin α5β1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights From Comprehensive Multicenter Preclinical Studies
Circulation|2025
23 cit.
8
FOXF1 promotes tumor vessel normalization and prevents lung cancer progression through FZD4
EMBO Molecular Medicine|2024
17 cit.
9
Hypusine Signaling Promotes Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension
American Journal of Respiratory and Critical Care Medicine|2024
14 cit.
10
Unraveling AURKB as a potential therapeutic target in pulmonary hypertension using integrated transcriptomic analysis and pre-clinical studies
Cell Reports Medicine|2025
8 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Khodr Tello
Universities of Giessen and Marburg Lung Center
2
Anton Vonk-Noordegraaf
Pulmonary Hypertension Association
3
Karin A. Boomars
Erasmus University Rotterdam
4
Paul D. Upton
University of Cambridge
5
Zhanqiang Li
Shaoguan University
6
Pavandeep Ghataorhe
GlaxoSmithKline (United Kingdom)
7
Kurt W. Prins
Medical University of South Carolina
8
Wei Huang
The Affiliated Yongchuan Hospital of Chongqing Medical University
9
Peter J. Leary
University of Washington
10
Partha Dutta
University of Pittsburgh

Papers

1
Guidelines for the Echocardiographic Assessment of the Right Heart in Adults and Special Considerations in Pulmonary Hypertension: Recommendations from the American Society of Echocardiography
Journal of the American Society of Echocardiography|2025
278 cit.
2
Ferroptosis-Mediated Inflammation Promotes Pulmonary Hypertension
Circulation Research|2024
77 cit.
3
Relevance of Cor Pulmonale in COPD With and Without Pulmonary Hypertension: A Retrospective Cohort Study
Frontiers in Cardiovascular Medicine|2022
64 cit.
4
Aberrant mitochondrial DNA synthesis in macrophages exacerbates inflammation and atherosclerosis
Nature Communications|2024
55 cit.
5
The evolution of survival of pulmonary arterial hypertension over 15 years
Pulmonary Circulation|2022
53 cit.
6
Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules
JACC Basic to Translational Science|2023
42 cit.
7
Pathophysiology of the right ventricle in health and disease: an update
Cardiovascular Research|2023
40 cit.
8
Loss of Amphiregulin drives inflammation and endothelial apoptosis in pulmonary hypertension
Life Science Alliance|2022
36 cit.
9
Prevalence and associations of sarcopenia, obesity and sarcopenic obesity in end-stage knee osteoarthritis patients
Journal of Health Population and Nutrition|2023
25 cit.
10
Peripheral Blood T Cells of Patients with IPAH Have a Reduced Cytokine-Producing Capacity
International Journal of Molecular Sciences|2022
23 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Gérald Simonneau
Inserm
2
Marius M. Hoeper
Medizinische Hochschule Hannover
3
Lewis J. Rubin
University of California San Diego
4
Marc Humbert
Inserm
5
Nelson B. Schiller
Hi-Z Technology (United States)
6
Anton Vonk Noordegraaf
Amsterdam University Medical Centers
7
Salvador Moncada
Universidad Autónoma de Madrid
8
Nicholas W. Morrell
University of Cambridge
9
Marlene Rabinovitch
Stanford Medicine
10
Norbert F. Voelkel
Amsterdam University Medical Centers

Papers

1
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
Nature|1987
10.8k cit.
2
Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography
Journal of the American Society of Echocardiography|2010
7k cit.
3
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
European Heart Journal|2015
7k cit.
4
Vascular endothelial cells synthesize nitric oxide from L-arginine
Nature|1988
4.8k cit.
5
2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
European Heart Journal|2022
3.7k cit.
6
An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
Nature|1976
3.6k cit.
7
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
European Respiratory Journal|2015
3.2k cit.
8
Bosentan Therapy for Pulmonary Arterial Hypertension
New England Journal of Medicine|2002
2.7k cit.
9
Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
Nature|1986
2.4k cit.
10
2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
European Respiratory Journal|2022
2.1k cit.

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