Leaderboards/Protease and Inhibitor Mechanisms

Protease and Inhibitor Mechanisms

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Papers

Publication in ACS Nano (2025) [26 citations, W4406170285]

ACS Nano|2025

26 cit.

Synthesis, biological assessment, and in silico binding mode interaction analyses and DFT studies of biphenylsulfonamide-based potent MMP-2 inhibitors effective against chronic myeloid leukemia

Journal of Molecular Structure|2024

19 cit.

Pinpointing prime structural attributes of potential MMP-2 inhibitors comprising alkyl/arylsulfonyl pyrrolidine scaffold: a ligand-based molecular modelling approach validated by molecular dynamics simulation analysis

SAR and QSAR in environmental research|2024

18 cit.

Biphenylsulfonamides as effective MMP‐2 inhibitors with promising antileukemic efficacy: Synthesis, in vitro biological evaluation, molecular docking, and MD simulation analysis

Drug Development Research|2024

13 cit.

Matrix metalloproteinase-8 (MMP-8) and its inhibitors: A minireview

European Journal of Medicinal Chemistry Reports|2024

12 cit.

CIAA: Integrated Proteomics and Structural Modeling for Understanding Cysteine Reactivity with Iodoacetamide Alkyne

ACS Chemical Biology|2025

3 cit.

Publication in Journal of Nanoparticle Research (2025) [W4408759610]

Journal of Nanoparticle Research|2025

0 cit.

Publication (2025) [W4413979091]

Unknown Journal|2025

0 cit.

Emerging Leaders

Drafting the new consensus

Papers

Edge‐Site Engineering of Defective Fe–N4 Nanozymes with Boosted Catalase‐Like Performance for Retinal Vasculopathies

Advanced Materials|2022

237 cit.

H2O2 Self‐Producing Single‐Atom Nanozyme Hydrogels as Light‐Controlled Oxidative Stress Amplifier for Enhanced Synergistic Therapy by Transforming “Cold” Tumors

Advanced Functional Materials|2022

200 cit.

A Thrombin‐Activated Peptide‐Templated Nanozyme for Remedying Ischemic Stroke via Thrombolytic and Neuroprotective Actions

Advanced Materials|2023

198 cit.

Ultrasmall metal alloy nanozymes mimicking neutrophil enzymatic cascades for tumor catalytic therapy

Nature Communications|2024

179 cit.

Chiral metal-organic frameworks incorporating nanozymes as neuroinflammation inhibitors for managing Parkinson’s disease

Nature Communications|2023

149 cit.

Nanozyme-based point-of-care testing: Revolutionizing environmental pollutant detection with high efficiency and low cost

Nano Today|2024

147 cit.

A hydrogen sulphide-responsive and depleting nanoplatform for cancer photodynamic therapy

Nature Communications|2022

138 cit.

A natural biogenic nanozyme for scavenging superoxide radicals

Nature Communications|2024

135 cit.

PET Imaging of Fibroblast Activation Protein in Various Types of Cancer Using68Ga-FAP-2286: Comparison with18F-FDG and68Ga-FAPI-46 in a Single-Center, Prospective Study

Journal of Nuclear Medicine|2022

110 cit.

Development of FAPI Tetramers to Improve Tumor Uptake and Efficacy of FAPI Radioligand Therapy

Journal of Nuclear Medicine|2023

99 cit.

Current Senior Leaders

Wrote the book, still writing it

Papers

Studies on transformation of Escherichia coli with plasmids

Journal of Molecular Biology|1983

11.3k cit.

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

Nature|1984

3.7k cit.

Requirement of Vascular Integrin α v β 3 for Angiogenesis

Science|1994

3k cit.

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

Nature Cell Biology|2000

2.8k cit.

A matrix metalloproteinase expressed on the surface of invasive tumour cells

Nature|1994

2.6k cit.

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Cell|1994

2.3k cit.

Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

Science|1998

2.1k cit.

Binding of soluble form of fibroblast surface protein, fibronectin, to collagen

International Journal of Cancer|1977

2k cit.

Induction of angiogenesis during the transition from hyperplasia to neoplasia

Nature|1989

1.9k cit.

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

Cell|1998

1.8k cit.

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Protease and Inhibitor Mechanisms

Rising Stars

Researchers

Papers

Emerging Leaders

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Papers

Current Senior Leaders

Researchers

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Reagents for Protease and Inhibitor Mechanisms

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