Leaderboards/Porphyrin Metabolism and Disorders

Porphyrin Metabolism and Disorders

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Aimee Rachel Mathew
Sapienza University of Rome
2
Nilesh Anand Devanand
Royal Adelaide Hospital
3
Jakob Ruickoldt
University of Potsdam
4
Mattias Lissing
Karolinska University Hospital
5
Romila Mascarenhas
University of Oregon
6
Sabiha Sultana
Carl von Ossietzky Universität Oldenburg
7
Sunisa Yoodee
Siriraj Hospital
8
Heidi L. Doden
University of Illinois Urbana-Champaign
9
Andreia Costa-Tuna
University of Coimbra
10
Laura D. Elmendorf
Stanford University

Papers

1
Vitamin B12 Deficiency and the Nervous System: Beyond Metabolic Decompensation—Comparing Biological Models and Gaining New Insights into Molecular and Cellular Mechanisms
International Journal of Molecular Sciences|2024
81 cit.
2
Profiling the Interaction between Human Serum Albumin and Clinically Relevant HIV Reverse Transcriptase Inhibitors
Viruses|2024
37 cit.
3
Large-scale identification of calcium oxalate stone inhibitory proteins in normal human urine
International Journal of Biological Macromolecules|2024
15 cit.
4
Defining physicochemical properties of urinary proteins that determine their inhibitory activities against calcium oxalate kidney stone formation
International Journal of Biological Macromolecules|2024
10 cit.
5
Publication in Archives of Biochemistry and Biophysics (2024) [5 citations, W4405402402]
Archives of Biochemistry and Biophysics|2024
5 cit.
6
Publication in Archives of Biochemistry and Biophysics (2025) [4 citations, W4409198311]
Archives of Biochemistry and Biophysics|2025
4 cit.
7
Vitamin B12 release through bacteriophage-mediated cell lysis of the marine bacterium <i>Sulfitobacter</i> sp. M39
ISME Communications|2025
4 cit.
8
Publication in International Journal of Biological Macromolecules (2025) [3 citations, W4409728532]
International Journal of Biological Macromolecules|2025
3 cit.
9
Publication in Biomedicine & Pharmacotherapy (2025) [2 citations, W4408778051]
Biomedicine & Pharmacotherapy|2025
2 cit.
10
An unusual Co–S bond links B <sub>12</sub> chaperones in an interprotein complex
Proceedings of the National Academy of Sciences|2025
2 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Stefan Hofbauer
BOKU University
2
Justin M. Kollman
University of Washington
3
Timothy Racie
Alnylam Pharmaceuticals (United States)
4
Janosch Klebensberger
University of Stuttgart
5
Jason M. Ridlon
University of Illinois Urbana-Champaign
6
Rabindra K. Behera
University of California, Berkeley
7
Hideyuki Kamisawa
Nagoya City University
8
Rei Unno
Nagoya City University
9
Amit R. Reddi
Georgia Institute of Technology
10
Lena J. Daumann
Heinrich Heine University Düsseldorf

Papers

1
Formation of secondary allo-bile acids by novel enzymes from gut Firmicutes
Gut Microbes|2022
60 cit.
2
Lanmodulin peptides – unravelling the binding of the EF-Hand loop sequences stripped from the structural corset
Inorganic Chemistry Frontiers|2022
54 cit.
3
IMPDH1 retinal variants control filament architecture to tune allosteric regulation
Nature Structural & Molecular Biology|2022
49 cit.
4
Human PRPS1 filaments stabilize allosteric sites to regulate activity
Nature Structural & Molecular Biology|2023
42 cit.
5
An expanded metabolic pathway for androgen production by commensal bacteria
Nature Microbiology|2025
31 cit.
6
Learning from nature: recovery of rare earth elements by the extremophilic bacterium <i>Methylacidiphilum fumariolicum</i>
Chemical Communications|2023
22 cit.
7
Exogenously Scavenged and Endogenously Synthesized Heme Are Differentially Utilized by Mycobacterium tuberculosis
Microbiology Spectrum|2022
19 cit.
8
Minor Actinides Can Replace Essential Lanthanides in Bacterial Life**
Angewandte Chemie International Edition|2023
19 cit.
9
Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin <scp>III</scp>: Propionate interactions and porphyrin core deformation
Protein Science|2022
16 cit.
10
Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation
Journal of Biological Chemistry|2023
16 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Kevin M. Smith
Louisiana State University
2
Rudolf K. Thauer
Max Planck Institute for Terrestrial Microbiology
3
Ruma Banerjee
University of Michigan
4
Robert J. Desnick
Icahn School of Medicine at Mount Sinai
5
Judith P. Klinman
QB3
6
Lechosław Latos‐Grażyński
Wrocław University of Science and Technology
7
Alison G. Smith
University of Cambridge
8
Jorge C. Escalante‐Semerena
University of Georgia
9
Luigi G. Marzilli
Emory University
10
Edward I. Solomon
SLAC National Accelerator Laboratory

Papers

1
Energy conservation in chemotrophic anaerobic bacteria
Bacteriological Reviews|1977
3.6k cit.
2
Energy conservation in chemotrophic anaerobic bacteria.
Bacteriological Reviews|1977
1.7k cit.
3
Safety and Efficacy of Recombinant Human α-Galactosidase A Replacement Therapy in Fabry's Disease
New England Journal of Medicine|2001
1.5k cit.
4
Algae acquire vitamin B12 through a symbiotic relationship with bacteria
Nature|2005
1.5k cit.
5
A Multiplet Analysis of Fe K-Edge 1s → 3d Pre-Edge Features of Iron Complexes
Journal of the American Chemical Society|1997
1.4k cit.
6
X-ray absorption edge determination of the oxidation state and coordination number of copper. Application to the type 3 site in Rhus vernicifera laccase and its reaction with oxygen
Journal of the American Chemical Society|1987
1k cit.
7
Pycnodysostosis, a Lysosomal Disease Caused by Cathepsin K Deficiency
Science|1996
1k cit.
8
High Incidence of Later-Onset Fabry Disease Revealed by Newborn Screening*
The American Journal of Human Genetics|2006
1k cit.
9
Oxygen Binding, Activation, and Reduction to Water by Copper Proteins
Angewandte Chemie International Edition|2001
831 cit.
10
Redox Biochemistry of Hydrogen Sulfide
Journal of Biological Chemistry|2010
749 cit.

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