Leaderboards/Plant-derived Lignans Synthesis and Bioactivity

Plant-derived Lignans Synthesis and Bioactivity

Last updated June 1, 2026

Rising Stars

New and hot

Rising Stars Researchers

1
Ki Sung Kang
Gachon University
85
2
Ersilia Nigro
University of Campania "Luigi Vanvitelli"
53
3
Yu Li
Nanjing University of Chinese Medicine
24

Rising Stars Papers

1
Liguzinediol potentiates the metabolic remodeling by activating the AMPK/SIRT3 pathway and represses Caspase-3/GSDME-mediated pyroptosis to ameliorate cardiotoxicity
Chinese Medicine|2024
4 cit.
2
Exploring the neuroprotective activity of a lignanamides-rich extract in human neuroblastoma SH-SY5Y cells under dimethyl sulfoxide-induced stress
Frontiers in Cell and Developmental Biology|2024
3 cit.
3
Attenuating Oxidative Damage with Macelignan in Glutamate-Induced HT22 Hippocampal Cells
Applied Sciences|2024
1 cit.
4
AdipoRon promotes angiogenesis in B-cell leukemia by modulating pro-angiogenic factors through AdipoR1
Molecular Biology Reports|2025
0 cit.

Emerging Leaders

Gaining momentum

Emerging Leaders Researchers

1
Lin‐Tao Xu
Shandong University of Traditional Chinese Medicine
99
2
M S Cho
Soonchunhyang University
95
3
Le Deng
Beijing Technology and Business University
79
4
Minjun Lee
Mokpo National University
50
5
Lü Jin
Soochow University
17
6
Xiao Yang
Guangdong Pharmaceutical University
13
7
Da Kyoung Oh
Unknown
8

Emerging Leaders Papers

1
Targeting SphK1/2 by SKI-178 inhibits prostate cancer cell growth
Cell Death and Disease|2023
19 cit.
2
Tussilagone attenuated cigarette smoke-induced chronic obstructive pulmonary disease through regulating Nrf2 and NF-κB/NLRP3 inflammasome via directly targeting cysteine 434 of KEAP1
Journal of Advanced Research|2025
2 cit.
3
Anti‐Lung Cancer Effects and Related Mechanisms of α‐Caryophyllene In Vitro and In Vivo
Food Science & Nutrition|2025
2 cit.
4
Evaluating the Potential Anti-Inflammatory Effects of Schisandra chinensis–Smilax china Extract in LPS-Induced RAW 264.7 Cells
Asian Journal of Beauty and Cosmetology|2025
0 cit.
5
Schisandrol B protects against lithocholic acid-induced cholestatic liver injury in mice through mitochondrial biogenesis
Chinese Medicine|2026
0 cit.
6
Targeting the ROS-JNK/p38 Axis: Schisandrin A as a Novel Therapeutic Candidate for Esophageal Squamous Cell Carcinoma
Journal of Microbiology and Biotechnology|2026
0 cit.
7
Quercetin–Arctigenin Co-Treatment Induces Mitochondrial Dysfunction and Apoptotic Cell Death Through Metabolic Stress in Malignant Mesothelioma Cells
Life|2026
0 cit.
8
Schisandrin B Attenuates PM2.5-Induced Pyroptosis via Caspase-1 Inhibition and Membrane Repair
Membranes|2026
0 cit.

All-Time Leaders

The canon

All-Time Leaders Researchers

1
Ruijie Liu
Walter and Eliza Hall Institute of Medical Research
92
2
Ning Gao
Army Medical University
78
3
Jie Zhao
Shanghai Jiao Tong University
77
4
Kyung‐Soo Nam
Dongguk University
75
5
Hongjuan Cui
Southwest University
75
6
Huichang Bi
Sun Yat-sen University
74
7
Yung Hyun Choi
Dong-Eui University
72
8
Shiqiang Yu
Xijing Hospital
71
9
Guoqing Zhang
Second Military Medical University
65
10
David Newman
Frederick National Laboratory for Cancer Research
62

All-Time Leaders Papers

1
Plants as a source of anti-cancer agents
Journal of Ethnopharmacology|2005
2k cit.
2
Targeting cancer stem cell pathways for cancer therapy
Signal Transduction and Targeted Therapy|2020
1.9k cit.
3
Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses
Nucleic Acids Research|2015
633 cit.
4
Biodiversity: A continuing source of novel drug leads
Pure and Applied Chemistry|2005
398 cit.
5
Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells
Scientific Reports|2018
264 cit.
6
Protective Effect of Glutathione against Oxidative Stress-induced Cytotoxicity in RAW 264.7 Macrophages through Activating the Nuclear Factor Erythroid 2-Related Factor-2/Heme Oxygenase-1 Pathway
Antioxidants|2019
190 cit.
7
Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells
Journal of Biomedical Science|2012
167 cit.
8
Polydopamine Nanoparticles Targeting Ferroptosis Mitigate Intervertebral Disc Degeneration Via Reactive Oxygen Species Depletion, Iron Ions Chelation, and GPX4 Ubiquitination Suppression
Advanced Science|2023
167 cit.
9
Honokiol Ameliorates Myocardial Ischemia/Reperfusion Injury in Type 1 Diabetic Rats by Reducing Oxidative Stress and Apoptosis through Activating the SIRT1‐Nrf2 Signaling Pathway
Oxidative Medicine and Cellular Longevity|2018
158 cit.
10
Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes
Nature Communications|2019
156 cit.

Indexing Plant-derived Lignans Synthesis and Bioactivity Reagents

Citation data for reagents in this field is currently compiling.