Leaderboards/PI3K

PI3K

Last updated May 19, 2026

Rising Stars

New and hot

Rising Stars Researchers

1
Julien Dilly
Broad Institute
672 cit.
2
Xianjing Chu
Xiangya Hospital Central South University
433 cit.
3
Christopher Gribben
Wellcome/MRC Cambridge Stem Cell Institute
336 cit.
4
Sheryl M. Gough
Arvinas (United States)
304 cit.
5
Lu Zhang
Shanghai Jiao Tong University
183 cit.
6
Amy E. Schade
Brigham and Women's Hospital
165 cit.
7
Yulan Ma
Wuhan University
162 cit.
8
Song Hee Lee
Seoul National University
153 cit.
9
Lynn Bonetti
University of Luxembourg
147 cit.
10
Ji Zhou
Unknown
135 cit.

Rising Stars Papers

1
Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer
Cancer Discovery|2024
223 cit.
2
Cancer stem cells: advances in knowledge and implications for cancer therapy
Signal Transduction and Targeted Therapy|2024
432 cit.
3
Acquisition of epithelial plasticity in human chronic liver disease
Nature|2024
111 cit.
4
Oral Estrogen Receptor PROTAC Vepdegestrant (ARV-471) Is Highly Efficacious as Monotherapy and in Combination with CDK4/6 or PI3K/mTOR Pathway Inhibitors in Preclinical ER+ Breast Cancer Models
Clinical Cancer Research|2024
151 cit.
5
The adhesin RadD enhances Fusobacterium nucleatum tumour colonization and colorectal carcinogenesis
Nature Microbiology|2024
72 cit.
6
AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution
Nature|2024
54 cit.
7
Semaglutide ameliorates cardiac remodeling in male mice by optimizing energy substrate utilization through the Creb5/NR4a1 axis
Nature Communications|2024
80 cit.
8
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation
Cell Communication and Signaling|2024
60 cit.
9
A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
Cell Metabolism|2024
48 cit.
10
Chrysotoxine regulates ferroptosis and the PI3K/AKT/mTOR pathway to prevent cervical cancer
Journal of Ethnopharmacology|2024
134 cit.

Rising Stars Reagents

Coming soon

Emerging Leaders

Gaining momentum

Emerging Leaders Researchers

1
Jian Zhang
Fudan University Shanghai Cancer Center
810 cit.
2
Bart Vanhaesebroeck
Cancer Research UK
147 cit.
3
Vadim N. Gladyshev
Brigham and Women's Hospital
143 cit.
4
Hui Zeng
Peking University Shenzhen Hospital
132 cit.
5
Hongbo Wang
Union Hospital
118 cit.
6
Jun Yu
Chinese University of Hong Kong
115 cit.
7
Zhijian Wei
Qilu Hospital of Shandong University
103 cit.
8
Patrízia Limonta
University of Milan
99 cit.
9
Christopher J. Tape
Cancer Research UK
94 cit.
10
Wei Yang
Sichuan University
83 cit.

Emerging Leaders Papers

1
NF-κB in biology and targeted therapy: new insights and translational implications
Signal Transduction and Targeted Therapy|2024
1.6k cit.
2
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration
Nature|2023
147 cit.
3
Distinct longevity mechanisms across and within species and their association with aging
Cell|2023
143 cit.
4
An injectable liposome-anchored teriparatide incorporated gallic acid-grafted gelatin hydrogel for osteoarthritis treatment
Nature Communications|2023
198 cit.
5
Histone lactylation promotes malignant progression by facilitating USP39 expression to target PI3K/AKT/HIF-1α signal pathway in endometrial carcinoma
Cell Death Discovery|2024
94 cit.
6
Traditional Medicine Pien Tze Huang Suppresses Colorectal Tumorigenesis Through Restoring Gut Microbiota and Metabolites
Gastroenterology|2023
172 cit.
7
Multifunctional Conductive and Electrogenic Hydrogel Repaired Spinal Cord Injury via Immunoregulation and Enhancement of Neuronal Differentiation
Advanced Materials|2024
103 cit.
8
The PI3K/Akt Pathway and Glucose Metabolism: A Dangerous Liaison in Cancer
International Journal of Biological Sciences|2024
197 cit.
9
An oncogenic phenoscape of colonic stem cell polarization
Cell|2023
94 cit.
10
A Gas Therapy Strategy for Intestinal Flora Regulation and Colitis Treatment by Nanogel‐Based Multistage NO Delivery Microcapsules
Advanced Materials|2024
83 cit.

Emerging Leaders Reagents

Coming soon

All-Time Leaders

The canon

All-Time Leaders Researchers

1
Jennifer A. Pietenpol
Vanderbilt University
16.4k cit.
2
Pasi A. Jänne
Massachusetts General Hospital
13.4k cit.
3
Alfred L. Goldberg
Harvard University
13.3k cit.
4
Valerie M. Weaver
University of California, San Francisco
12k cit.
5
Richard A. Miller
University of Michigan
11.2k cit.
6
Craig B. Thompson
University of Pennsylvania
10.2k cit.
7
David J. Glass
Unknown
5.8k cit.
8
Dihua Yu
The University of Texas MD Anderson Cancer Center
5.6k cit.
9
Steven E. Arnold
University of Pennsylvania
5.5k cit.
10
René Bernards
The Netherlands Cancer Institute
4.9k cit.

All-Time Leaders Papers

1
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
Journal of Clinical Investigation|2011
5.5k cit.
2
<i>MET</i> Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
Science|2007
4.5k cit.
3
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
Cell|2009
4k cit.
4
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
Nature|2009
3.7k cit.
5
The Molecular Taxonomy of Primary Prostate Cancer
Cell|2015
3.2k cit.
6
Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
Cell|2004
3k cit.
7
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
Proceedings of the National Academy of Sciences|2008
2k cit.
8
The IGF-1/PI3K/Akt Pathway Prevents Expression of Muscle Atrophy-Induced Ubiquitin Ligases by Inhibiting FOXO Transcription Factors
Molecular Cell|2004
1.9k cit.
9
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
Cancer Cell|2004
1.9k cit.
10
Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
Journal of Clinical Investigation|2012
1.8k cit.

All-Time Leaders Reagents

Coming soon

Indexing PI3K Reagents

Citation data for reagents in this field is currently compiling.