Leaderboards/Phagocytosis and Immune Regulation

Phagocytosis and Immune Regulation

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Konrad Hoeft
RWTH Aachen University
2
Anhua Lei
National Science Centre
3
Hongxu Xian
National University of Singapore
4
Sophia Maschalidi
Ghent University
5
Peng Zhang
Northwestern University
6
Zhaohan Wei
Shenzhen University Health Science Center
7
Federico F. De Ponti
VIB-UGent Center for Inflammation Research
8
Haiwei Ni
Baylor College of Medicine
9
Kelvin Ka-lok Wu
Hong Kong Polytechnic University
10
Serena Omo‐Lamai
University of Pennsylvania

Papers

1
Physicochemical Targeting of Lipid Nanoparticles to the Lungs Induces Clotting: Mechanisms and Solutions
Advanced Materials|2024
101 cit.
2
Publication in Nature Cancer (2025) [60 citations, W4407164174]
Nature Cancer|2025
60 cit.
3
Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape
Nature Nanotechnology|2025
55 cit.
4
ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts
Journal of Clinical Investigation|2024
19 cit.
5
Mitochondrial DNA oxidation propagates autoimmunity by enabling plasmacytoid dendritic cells to induce TFH differentiation
Nature Immunology|2025
14 cit.
6
Targeting of nanoparticles to the cerebral vasculature after traumatic brain injury
PLoS ONE|2024
12 cit.
7
Publication in Nature Reviews Bioengineering (2025) [8 citations, W4410302308]
Nature Reviews Bioengineering|2025
8 cit.
8
Label-free single-cell RNA multiplexing leveraging genetic variability
Nature Communications|2024
3 cit.
9
Circulating oxidized mitochondrial DNA drives autoimmunity
The Journal of Immunology|2024
1 cit.
10
Multimodal Atlas of Human Heart Failure with Preserved Ejection Fraction
Journal of the American Society of Nephrology|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Kiril Bidzhekov
Ludwig-Maximilians-Universität München
2
Rushika M. Perera
University of California, San Francisco
3
Arnaud Jabouille
Université de Bordeaux
4
Oliver Florey
Babraham Institute
5
Benjamin Izar
Columbia University Irving Medical Center
6
Nicholas Arpaia
Columbia University Irving Medical Center
7
Shiyu Liu
Air Force Medical University
8
Jing Huang
Westlake University
9
Xu Li
Westlake University
10
Lizhu Lin
Guangzhou University of Chinese Medicine

Papers

1
Targeting M2-like tumor-associated macrophages is a potential therapeutic approach to overcome antitumor drug resistance
npj Precision Oncology|2024
493 cit.
2
Dissecting the treatment-naive ecosystem of human melanoma brain metastasis
Cell|2022
211 cit.
3
V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy
The Journal of Cell Biology|2022
171 cit.
4
Probiotic neoantigen delivery vectors for precision cancer immunotherapy
Nature|2024
158 cit.
5
Chemokines expressed by engineered bacteria recruit and orchestrate antitumor immunity
Science Advances|2023
154 cit.
6
Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis
Immunity|2024
98 cit.
7
Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy
The Journal of Cell Biology|2023
95 cit.
8
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity
Cancer Cell|2023
94 cit.
9
Regulation of the alveolar regenerative niche by amphiregulin-producing regulatory T cells
The Journal of Experimental Medicine|2022
70 cit.
10
Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens
Nature Genetics|2023
59 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Peter M. Henson
National Jewish Health
2
Irving L. Weissman
California Institute for Regenerative Medicine
3
Shigekazu Nagata
The University of Osaka
4
Guido Kroemer
Institut Universitaire de France
5
Douglas R. Green
St. Jude Children's Research Hospital
6
Kodi S. Ravichandran
Washington University in St. Louis
7
Ira Tabas
Columbia University Irving Medical Center
8
Vishva M. Dixit
Molecular Oncology (United States)
9
Craig B. Thompson
Memorial Sloan Kettering Cancer Center
10
Greg Lemke
Salk Institute for Biological Studies

Papers

1
Autophagy in the Pathogenesis of Disease
Cell|2008
7k cit.
2
Molecular characterization of mitochondrial apoptosis-inducing factor
Nature|1999
4k cit.
3
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nature|2015
3.7k cit.
4
The Pathophysiology of Mitochondrial Cell Death
Science|2004
3.4k cit.
5
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
Cell Death and Differentiation|2008
3.3k cit.
6
Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
The Journal of Immunology|1992
3.3k cit.
7
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
Nature|1998
3.2k cit.
8
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
Journal of Clinical Investigation|1998
3.1k cit.
9
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
Cell|1993
3.1k cit.
10
Calreticulin exposure dictates the immunogenicity of cancer cell death
Nature Medicine|2006
3.1k cit.

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