Leaderboards/NF-κB Signaling Pathways

NF-κB Signaling Pathways

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Jared T. Hinkle
Johns Hopkins University
2
Xiu-Ming Li
Soochow University
3
Jack A. Prescott
Babraham Institute
4
Md. Saddam
Gopalganj Science and Technology University
5
Yuxi Cheng
Sun Yat-sen University
6
Jelena Petković-Dabić
University of Banja Luka
7
Hector Flores‐Romero
Ikerbasque
8
Guangyu Xu
Hebei Medical University
9
Wenmiao He
Nanjing Medical University
10
Milton Pereira
Universidade Federal de Minas Gerais

Papers

1
Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
Cell Reports|2024
105 cit.
2
Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting
Cell Reports|2024
72 cit.
3
Publication in The Science of The Total Environment (2024) [59 citations, W4392148134]
The Science of The Total Environment|2024
59 cit.
4
The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
Cell Reports|2024
12 cit.
5
Publication in Ecotoxicology and Environmental Safety (2024) [8 citations, W4402984812]
Ecotoxicology and Environmental Safety|2024
8 cit.
6
Publication in Environmental Science & Technology (2025) [6 citations, W4412111897]
Environmental Science & Technology|2025
6 cit.
7
Publication in Journal of Huntington s Disease (2024) [1 citation, W4402407945]
Journal of Huntington s Disease|2024
1 cit.
8
Publication in International Journal of Environmental Research and Public Health (2025) [W4412475239]
International Journal of Environmental Research and Public Health|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Shaun Conway
Unknown
2
Han Qiao
Shanghai Jiao Tong University
3
Ganzhen Deng
Huazhong Agricultural University
4
Feng Qian
Merck & Co., Inc., Rahway, NJ, USA (United States)
5
Cliff Y. Yang
Sun Yat-sen University
6
Xiangliang Deng
Guangdong Pharmaceutical University
7
Ai-Qing Yu
Hubei University of Medicine
8
Yunhe Fu
Jilin University
9
Zecai Zhang
Heilongjiang Bayi Agricultural University
10
Yunfei Qin
Sun Yat-sen University

Papers

1
H3K18 lactylation of senescent microglia potentiates brain aging and Alzheimer's disease through the NFκB signaling pathway
Journal of Neuroinflammation|2023
223 cit.
2
Commensal cow Roseburia reduces gut-dysbiosis-induced mastitis through inhibiting bacterial translocation by producing butyrate in mice
Cell Reports|2022
133 cit.
3
The Rumen Microbiota Contributes to the Development of Mastitis in Dairy Cows
Microbiology Spectrum|2022
123 cit.
4
Gut microbiota-mediated secondary bile acid alleviates Staphylococcus aureus-induced mastitis through the TGR5-cAMP-PKA-NF-κB/NLRP3 pathways in mice
npj Biofilms and Microbiomes|2023
121 cit.
5
Gut/rumen-mammary gland axis in mastitis: Gut/rumen microbiota–mediated “gastroenterogenic mastitis”
Journal of Advanced Research|2023
59 cit.
6
Staphylococcal virulence factor HlgB targets the endoplasmic-reticulum-resident E3 ubiquitin ligase AMFR to promote pneumonia
Nature Microbiology|2023
35 cit.
7
Immune-regulating strategy against rheumatoid arthritis by inducing tolerogenic dendritic cells with modified zinc peroxide nanoparticles
Journal of Nanobiotechnology|2022
27 cit.
8
Blockade of the mitochondrial DNA release ameliorates hepatic ischemia-reperfusion injury through avoiding the activation of cGAS-Sting pathway
Journal of Translational Medicine|2024
27 cit.
9
Formononetin Protects LPS-Induced Mastitis Through Suppressing Inflammation and Enhancing Blood-Milk Barrier Integrity via AhR-Induced Src Inactivation
Frontiers in Immunology|2022
26 cit.
10
Macrophage LMO7 deficiency facilitates inflammatory injury via metabolic-epigenetic reprogramming
Acta Pharmaceutica Sinica B|2023
25 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Michael Karin
Discovery Institute
2
David Baltimore
California Institute of Technology
3
Shizuo Akira
Kunsan National University
4
Albert S. Baldwin
University of North Carolina at Chapel Hill
5
Bharat B. Aggarwal
Max Super Speciality Hospital
6
Vishva M. Dixit
Molecular Oncology (United States)
7
Patrick A. Baeuerle
C4 Therapeutics (United States)
8
Shao‐Cong Sun
Capital Medical University
9
Sankar Ghosh
Columbia University Irving Medical Center
10
Roger J. Davis
University of Massachusetts Chan Medical School

Papers

1
NF-κB signaling in inflammation
Signal Transduction and Targeted Therapy|2017
8.1k cit.
2
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
Proceedings of the National Academy of Sciences|2006
4.3k cit.
3
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
Nature|2006
3.8k cit.
4
Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.
The EMBO Journal|1991
3.8k cit.
5
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nature|2015
3.7k cit.
6
Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the <i>Lps</i> Gene Product
The Journal of Immunology|1999
3.4k cit.
7
Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components
Immunity|1999
3.4k cit.
8
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
Cell|1994
3.2k cit.
9
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
Science|2003
3.2k cit.
10
An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death
Science|1996
3.1k cit.

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