Leaderboards/Metalloenzymes and iron-sulfur proteins

Metalloenzymes and iron-sulfur proteins

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Joseph A. Mattocks
Pennsylvania State University
2
Margaret Dreishpoon
Broad Institute
3
Vinzent Schulz
Loewe Center for Synthetic Microbiology
4
Alexander Katsyv
Goethe University Frankfurt
5
Sylvain Gervason
AgroParisTech
6
Jewelianna M. Moore
Texas A&M University
7
Kai-Peng Hou
University of California, San Francisco
8
Andrea Fasano
Centre National de la Recherche Scientifique
9
Yudhajeet Basak
Humboldt-Universität zu Berlin
10
Victor M. Ruiz-Arroyo
The University of Texas Southwestern Medical Center

Papers

1
Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2
Nature Communications|2024
29 cit.
2
Publication in Journal of the American Chemical Society (2024) [26 citations, W4390493176]
Journal of the American Chemical Society|2024
26 cit.
3
Publication in ACS Catalysis (2024) [15 citations, W4394951090]
ACS Catalysis|2024
15 cit.
4
Publication in Current Opinion in Electrochemistry (2024) [11 citations, W4393953294]
Current Opinion in Electrochemistry|2024
11 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Gustav Berggren
Technische Universität Berlin
2
Chris Greening
Australian Regenerative Medicine Institute
3
James A. Birrell
University of Essex
4
Lena J. Daumann
Heinrich Heine University Düsseldorf
5
Arnab Dutta
Indian Institute of Technology Bombay
6
Niklas B. Thompson
University of Chicago
7
Jan M. Schuller
Loewe Center for Synthetic Microbiology
8
Tatiana N. Laremore
Pennsylvania State University
9
Huai‐Qiang Ju
Sun Yat-sen University
10
Wei‐chen Chang
North Carolina State University

Papers

1
Methionine deficiency facilitates antitumour immunity by altering m<sup>6</sup>A methylation of immune checkpoint transcripts
Gut|2022
215 cit.
2
Phylogenetically and catabolically diverse diazotrophs reside in deep-sea cold seep sediments
Nature Communications|2022
132 cit.
3
Membrane-anchored HDCR nanowires drive hydrogen-powered CO2 fixation
Nature|2022
97 cit.
4
Structural basis for bacterial energy extraction from atmospheric hydrogen
Nature|2023
86 cit.
5
Molecular hydrogen in seawater supports growth of diverse marine bacteria
Nature Microbiology|2023
78 cit.
6
Molecular Basis of the Electron Bifurcation Mechanism in the [FeFe]-Hydrogenase Complex HydABC
Journal of the American Chemical Society|2023
69 cit.
7
A Janus cerium-doped bismuth oxide electrocatalyst for complete water splitting
Cell Reports Physical Science|2022
66 cit.
8
The liver microenvironment orchestrates FGL1-mediated immune escape and progression of metastatic colorectal cancer
Nature Communications|2023
62 cit.
9
A nitrite-oxidising bacterium constitutively consumes atmospheric hydrogen
The ISME Journal|2022
59 cit.
10
The Macrophage-Associated LncRNA <i>MALR</i> Facilitates ILF3 Liquid–Liquid Phase Separation to Promote HIF1α Signaling in Esophageal Cancer
Cancer Research|2022
58 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Jonas C. Peters
California Institute of Technology
2
Douglas C. Rees
California Institute of Technology
3
Dennis R. Dean
Virginia Tech
4
Marc Fontecave
Centre National de la Recherche Scientifique
5
Vincent Artero
Centre National de la Recherche Scientifique
6
Roland Lill
Philipps University of Marburg
7
Brian M. Hoffman
Northwestern University
8
Thomas B. Rauchfuss
University of Illinois System
9
Fräser A. Armstrong
St. John's College
10
Wolfgang Lubitz
Max Planck Institute for Chemical Energy Conversion

Papers

1
Nitrogenase MoFe-Protein at 1.16 Å Resolution: A Central Ligand in the FeMo-Cofactor
Science|2002
1.1k cit.
2
Structural Basis of Biological Nitrogen Fixation
Chemical Reviews|1996
1k cit.
3
The <i>E. coli</i> BtuCD Structure: A Framework for ABC Transporter Architecture and Mechanism
Science|2002
1k cit.
4
Catalytic conversion of nitrogen to ammonia by an iron model complex
Nature|2013
999 cit.
5
Structure of the MscL Homolog from <i>Mycobacterium tuberculosis</i> : A Gated Mechanosensitive Ion Channel
Science|1998
989 cit.
6
From Hydrogenases to Noble Metal–Free Catalytic Nanomaterials for H <sub>2</sub> Production and Uptake
Science|2009
941 cit.
7
Structure of the reaction center from Rhodobacter sphaeroides R-26: the cofactors.
Proceedings of the National Academy of Sciences|1987
916 cit.
8
Structural Models for the Metal Centers in the Nitrogenase Molybdenum-Iron Protein
Science|1992
834 cit.
9
A Janus cobalt-based catalytic material for electro-splitting of water
Nature Materials|2012
831 cit.
10
Heparin Structure and Interactions with Basic Fibroblast Growth Factor
Science|1996
804 cit.

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