Leaderboards/Ion channel regulation and function

Ion channel regulation and function

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Venkata S. Mandala
Rockefeller University
2
Mohammad‐Reza Ghovanloo
Yale University
3
Yiqing Wei
Chinese Academy of Sciences
4
Paola Peinado
Universidad de Granada
5
Ryan Mahling
Columbia University
6
Xiangchan Hou
Central South University
7
Rose Z. Hill
Howard Hughes Medical Institute
8
Thaila Kawane Euflazio Maximiano
Universidade Estadual de Londrina
9
Xin Rui Lim
University of Vermont
10
Verena Burtscher
Washington University in St. Louis

Papers

1
Publication in PLoS Biology (2024) [78 citations, W4399907760]
PLoS Biology|2024
78 cit.
2
Publication in Cell Calcium (2024) [69 citations, W4392626799]
Cell Calcium|2024
69 cit.
3
Publication in Cell (2024) [56 citations, W4392980203]
Cell|2024
56 cit.
4
Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow
Nature Communications|2024
55 cit.
5
Publication in Nature Communications (2024) [32 citations, W4393343312]
Nature Communications|2024
32 cit.
6
Publication in Proceedings of the National Academy of Sciences (2025) [18 citations, W4406669137]
Proceedings of the National Academy of Sciences|2025
18 cit.
7
Publication in Cell (2025) [16 citations, W4413276894]
Cell|2025
16 cit.
8
Publication in Communications Biology (2024) [10 citations, W4391130483]
Communications Biology|2024
10 cit.
9
Amyloid beta Aβ1-40 activates Piezo1 channels in brain capillary endothelial cells
Biophysical Journal|2024
6 cit.
10
Electric field–induced pore constriction in the human K <sub>v</sub> 2.1 channel
Proceedings of the National Academy of Sciences|2025
5 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Zhangqiang Li
Laboratoire de Biologie Physico-Chimique des Protéines Membranaires
2
Ryan Hibbs
University of California San Diego
3
Huaizong Shen
Beijing Advanced Sciences and Innovation Center
4
Chao Chang
Peking University
5
Stephan A. Pless
University of Copenhagen
6
Kate Poole
UNSW Sydney
7
Stephen G. Brohawn
QB3
8
Valeria Vásquez
The University of Texas Health Science Center
9
Alexander T. Chesler
National Institutes of Health
10
Zhaozhu Qiu
Johns Hopkins University

Papers

1
Terahertz Photons Improve Cognitive Functions in Posttraumatic Stress Disorder
Research|2023
121 cit.
2
An ultra-sensitive metasurface biosensor for instant cancer detection based on terahertz spectra
Nano Research|2023
99 cit.
3
Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities
Nature Communications|2022
95 cit.
4
ATP-releasing SWELL1 channel in spinal microglia contributes to neuropathic pain
Science Advances|2023
94 cit.
5
Structure of SARS-CoV-2 M protein in lipid nanodiscs
eLife|2022
85 cit.
6
Structural mechanism of muscle nicotinic receptor desensitization and block by curare
Nature Structural & Molecular Biology|2022
83 cit.
7
Inhibition of Cancer Cell Migration and Glycolysis by Terahertz Wave Modulation via Altered Chromatin Accessibility
Research|2022
75 cit.
8
Structural mechanisms of GABAA receptor autoimmune encephalitis
Cell|2022
73 cit.
9
Structural insights into opposing actions of neurosteroids on GABAA receptors
Nature Communications|2023
73 cit.
10
Ventral tegmental area astrocytes modulate cocaine reward by tonically releasing GABA
Neuron|2023
63 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Roderick MacKinnon
Howard Hughes Medical Institute
2
William A. Catterall
Dartmouth Institute for Health Policy and Clinical Practice
3
David Julius
University of California, San Francisco
4
Richard W. Tsien
NYU Langone Health
5
Bert Sakmann
Max Planck Institute for Intelligent Systems
6
Thomas J. Jentsch
Leibniz-Forschungsinstitut für Molekulare Pharmakologie
7
Lily Yeh Jan
University of California, San Francisco
8
Stephen G. Waxman
Yale University
9
David E. Clapham
Janelia Research Campus
10
Donald M. Bers
University of California, Davis

Papers

1
The capsaicin receptor: a heat-activated ion channel in the pain pathway
Nature|1997
9.1k cit.
2
The Structure of the Potassium Channel: Molecular Basis of K <sup>+</sup> Conduction and Selectivity
Science|1998
6.8k cit.
3
Regulation of Synaptic Efficacy by Coincidence of Postsynaptic APs and EPSPs
Science|1997
3.9k cit.
4
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
Science|2000
3.5k cit.
5
The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli
Neuron|1998
3.1k cit.
6
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
Nature|2002
2.7k cit.
7
Single-channel currents recorded from membrane of denervated frog muscle fibres
Nature|1976
2.5k cit.
8
Three types of neuronal calcium channel with different calcium agonist sensitivity
Nature|1985
2.2k cit.
9
Crystal Structure of a Mammalian Voltage-Dependent <i>Shaker</i> Family K <sup>+</sup> Channel
Science|2005
2.1k cit.
10
Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution
Nature|2001
2.1k cit.

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