Leaderboards/HIV/AIDS drug development and treatment

HIV/AIDS drug development and treatment

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Tom Loosli
University Hospital of Zurich
2
Natalie F. McMyn
Johns Hopkins University
3
Axel Cyriaque Ambassa
Université de Yaoundé I
4
Debora Chiodi
Takeda (United States)
5
Manish Gupta
Chicago Institute for Psychoanalysis
6
Xiangkai Ji
Shandong University
7
Anca-Denise Ciută
ETH Zurich
8
Jae-Hyun Park
Sungkyunkwan University
9
Shimona Starling
NatureServe
10
Akshay Deshpande
Ben-Gurion University of the Negev

Papers

1
Publication in European Journal of Medicinal Chemistry (2024) [65 citations, W4393942216]
European Journal of Medicinal Chemistry|2024
65 cit.
2
Predicted dolutegravir resistance in people living with HIV in South Africa during 2020–35: a modelling study
The Lancet Global Health|2025
24 cit.
3
Drug Resistance in People With Viremia on Dolutegravir-based Antiretroviral Therapy in Sub-Saharan Africa: The DTG RESIST Study
Clinical Infectious Diseases|2025
11 cit.
4
Publication in Science Advances (2025) [5 citations, W4409493813]
Science Advances|2025
5 cit.
5
Factors associated with resistance of HIV-1 reservoir viruses to neutralization by autologous IgG antibodies
Journal of Clinical Investigation|2025
5 cit.
6
Publication in Proceedings of the National Academy of Sciences (2026) [4 citations, W7134920150]
Proceedings of the National Academy of Sciences|2026
4 cit.
7
Korea-Japan Biophysics Collaboration: A journey through microbial rhodopsin research
Biophysics and Physicobiology|2025
0 cit.
8
Publication in RSC Medicinal Chemistry (2026) [W7124831085]
RSC Medicinal Chemistry|2026
0 cit.
9
Publication in University of Chicago (2026) [W7163026328]
University of Chicago|2026
0 cit.
10
Publication in University of Chicago (2026) [W7163042850]
University of Chicago|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Hal Martin
Gilead Sciences (United States)
2
Yunkai Yu
Zhejiang University of Science and Technology
3
Hao Yang
Tongji University
4
Anna Fryszkowska
Merck & Co., Inc., Rahway, NJ, USA (United States)
5
Sean E Collins
Gilead Sciences (United States)
6
Ya‐Chi Ho
Yale University
7
Dongwei Kang
Shandong University
8
Moupali Das
University of California, San Francisco
9
Chunlin Zhuang
Second Military Medical University
10
Malte Braunschweig
University of Freiburg

Papers

1
Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones
Immunity|2022
170 cit.
2
Single-cell epigenetic, transcriptional, and protein profiling of latent and active HIV-1 reservoir revealed that IKZF3 promotes HIV-1 persistence
Immunity|2023
68 cit.
3
A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins
Science|2022
55 cit.
4
A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease
Redox Biology|2023
50 cit.
5
mRNA vaccine-induced antibodies more effective than natural immunity in neutralizing SARS-CoV-2 and its high affinity variants
Scientific Reports|2022
44 cit.
6
Crystallography-Guided Optimizations of the Keap1–Nrf2 Inhibitors on the Solvent Exposed Region: From Symmetric to Asymmetric Naphthalenesulfonamides
Journal of Medicinal Chemistry|2022
29 cit.
7
Integration site–dependent HIV-1 promoter activity shapes host chromatin conformation
Genome Research|2023
28 cit.
8
Targeting Receptor-Interacting Protein Kinase 1 by Novel Benzothiazole Derivatives: Treatment of Acute Lung Injury through the Necroptosis Pathway
Journal of Medicinal Chemistry|2023
26 cit.
9
Greening Oxidation Catalysis: Water as a Solvent for Efficient Alkene Epoxidation over a Titanosilicate/H<sub>2</sub>O<sub>2</sub> System
ACS Sustainable Chemistry & Engineering|2022
21 cit.
10
O-GlcNAcylation of NLRP3 Contributes to Lipopolysaccharide-Induced Pyroptosis of Human Gingival Fibroblasts
Molecular Biotechnology|2023
20 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Arthur J. Olson
Scripps Research Institute
2
Erik De Clercq
Rega Institute for Medical Research
3
Robert F. Siliciano
Howard Hughes Medical Institute
4
Nathaniel R. Landau
New York University
5
Joseph Sodroski
Harvard University
6
Douglas D. Richman
University of San Diego
7
David D. Ho
Columbia University
8
Dennis R. Burton
Scripps Research Institute
9
Mark A. Wainberg
Jewish General Hospital
10
Hiroaki Mitsuya
National Institute of Technology, Kumamoto College

Papers

1
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
Journal of Computational Chemistry|2009
37.1k cit.
2
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
Journal of Computational Chemistry|2009
25k cit.
3
Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function
Journal of Computational Chemistry|1998
10.8k cit.
4
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
Nature|1995
4.3k cit.
5
Small-Molecule Library Screening by Docking with PyRx
Methods in molecular biology|2014
3.9k cit.
6
Identification of a major co-receptor for primary isolates of HIV-1
Nature|1996
3.7k cit.
7
HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time
Science|1996
3.5k cit.
8
Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy
Science|1997
3.1k cit.
9
Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection
Cell|1996
3.1k cit.
10
Computational protein–ligand docking and virtual drug screening with the AutoDock suite
Nature Protocols|2016
2.7k cit.

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