Leaderboards/Histone Deacetylase Inhibitors Research

Histone Deacetylase Inhibitors Research

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Deblina Raychaudhuri
The University of Texas MD Anderson Cancer Center
2
Ethan S. Toriki
Novartis (Switzerland)
3
Grace Q. Gong
London Cancer
4
Martina Lepore Signorile
Gastroenterology Hospital "Saverio de Bellis"
5
Edmond R. Watson
Bristol-Myers Squibb (Germany)
6
Mengdie Dong
Nantong University
7
Megan J. R. Yeo
Broad Institute
8
Zhifan Mao
East China University of Science and Technology
9
Tina Šket
National Institute of Chemistry
10
Al‐Hassan M. Mustafa
Johannes Gutenberg University Mainz

Papers

1
Publication in Nature Immunology (2024) [154 citations, W4403194835]
Nature Immunology|2024
154 cit.
2
Precision Targeting of Mutant PI3Kα
Cancer Discovery|2024
6 cit.
3
ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding
Biochemical Journal|2024
3 cit.
4
Publication in Cancer Research (2025) [W4409633520]
Cancer Research|2025
0 cit.
5
Mezigdomide overcomes CRBN mutations emerging post IMiD therapy
Blood|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Di Zhang
Shandong University of Technology
2
Ing Soo Tiong
The University of Melbourne
3
Qiang You
Second Affiliated Hospital of Nanjing Medical University
4
Haobin Ye
Fudan University
5
Anna Krug
University of Colorado Anschutz Medical Campus
6
Dongming Xing
Qingdao University
7
Eric S. Fischer
Dana-Farber Cancer Institute
8
Katrien De Bock
ETH Zurich
9
Kang Xu
Hubei University of Chinese Medicine
10
Jonathan D. Lee
Harvard University Press

Papers

1
Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells
Pharmacological Research|2022
372 cit.
2
The Current and Future Perspectives of Postbiotics
Probiotics and Antimicrobial Proteins|2023
175 cit.
3
Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites
Phytomedicine|2023
168 cit.
4
Lysine l-lactylation is the dominant lactylation isomer induced by glycolysis
Nature Chemical Biology|2024
140 cit.
5
Lumican promotes calcific aortic valve disease through H3 histone lactylation
European Heart Journal|2024
108 cit.
6
Andrographolide regulates H3 histone lactylation by interfering with p300 to alleviate aortic valve calcification
British Journal of Pharmacology|2024
86 cit.
7
MME+ fibro-adipogenic progenitors are the dominant adipogenic population during fatty infiltration in human skeletal muscle
Communications Biology|2023
73 cit.
8
Gut microbiota‐derived butyric acid regulates calcific aortic valve disease pathogenesis by modulating GAPDH lactylation and butyrylation
iMeta|2025
67 cit.
9
Chitinase-3 like-protein-1 promotes glioma progression via the NF-κB signaling pathway and tumor microenvironment reprogramming
Theranostics|2022
66 cit.
10
Biomimetic cascade nanoreactor with triple-enzyme mimetic activities for colorimetric detection of acid phosphatase
Chemical Engineering Journal|2022
49 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Eric N. Olson
Southwestern Medical Center
2
Yue Xiong
University of North Carolina at Chapel Hill
3
Stuart L. Schreiber
Broad Institute
4
Craig B. Thompson
Memorial Sloan Kettering Cancer Center
5
Ronald M. Evans
University of California San Diego
6
Stefan Knapp
Goethe University Frankfurt
7
Yi Zhang
Sun Yat-sen University
8
Kun‐Liang Guan
Westlake University
9
Kenneth C. Anderson
Dana-Farber Cancer Institute
10
Kapil N. Bhalla
The University of Texas MD Anderson Cancer Center

Papers

1
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Nature Cell Biology|2011
7k cit.
2
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
Cell|1991
4.1k cit.
3
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
Cell|2003
3.9k cit.
4
Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing
Science|2002
3.8k cit.
5
Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
Science|2011
3.4k cit.
6
p21 is a universal inhibitor of cyclin kinases
Nature|1993
3.4k cit.
7
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Genes & Development|2007
3.2k cit.
8
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
Cell|1993
3.1k cit.
9
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
Nature Cell Biology|2002
3.1k cit.
10
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
Cell|1995
2.9k cit.

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