Leaderboards/High Altitude and Hypoxia

High Altitude and Hypoxia

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Wenjin Sun
Sichuan University
2
Wangshan Zheng
Lanzhou Jiaotong University
3
Maciej Jaśkiewicz
Gdańsk Medical University
4
Elijah S. Lawrence
University of California San Diego
5
Fei Wu
Buck Institute for Research on Aging
6
Clément Lévêque
Université de Bretagne Occidentale
7
Nadia Houerbi
California Institute of Technology
8
Meiquan Li
Kunming University
9
Christian Arias‐Reyes
Institut universitaire de cardiologie et de pneumologie de Québec
10
Huxinyue Duan
Chengdu University of Traditional Chinese Medicine

Papers

1
Functional <i>EPAS1</i> / <i>HIF2A</i> missense variant is associated with hematocrit in Andean highlanders
Science Advances|2024
36 cit.
2
Publication in iScience (2025) [2 citations, W4411341861]
iScience|2025
2 cit.
3
Publication in Probiotics and Antimicrobial Proteins (2024) [1 citation, W4390886195]
Probiotics and Antimicrobial Proteins|2024
1 cit.
4
Publication in Genomics (2025) [1 citation, W4412450412]
Genomics|2025
1 cit.
5
Publication in Genes (2025) [1 citation, W4412762395]
Genes|2025
1 cit.
6
Publication in Frontiers in Animal Science (2025) [W4410485274]
Frontiers in Animal Science|2025
0 cit.
7
High-altitude thrombosis: divergent pathophysiological mechanisms and preventive strategies in acutely exposed population and native highlanders
Frontiers in Cardiovascular Medicine|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Eric Erquan Zhang
National Institute of Biological Sciences, Beijing
2
Deepa Shukla
Metabolism and Renal Physiology
3
Yacong He
Chengdu University of Traditional Chinese Medicine
4
Zhenxing Wang
Southwest Forestry University
5
Shengguo Zhao
Chinese Academy of Agricultural Sciences
6
Yao Hu
West China Medical Center of Sichuan University
7
Christopher R. Brandner
Aspire Academy
8
Xiaobo Wang
Hebei University
9
Joan Ramón Torrella
Universitat de Barcelona
10
J.E. Yu
Beijing Forestry University

Papers

1
Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals
Cell|2023
239 cit.
2
Sipeimine ameliorates PM2.5-induced lung injury by inhibiting ferroptosis via the PI3K/Akt/Nrf2 pathway: A network pharmacology approach
Ecotoxicology and Environmental Safety|2022
71 cit.
3
Salidroside intensifies mitochondrial function of CoCl2-damaged HT22 cells by stimulating PI3K-AKT-MAPK signaling pathway
Phytomedicine|2022
69 cit.
4
Sodium butyrate promotes gastrointestinal development of preweaning bull calves via inhibiting inflammation, balancing nutrient metabolism, and optimizing microbial community functions
Animal nutrition|2023
67 cit.
5
Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling
Biomedicine & Pharmacotherapy|2022
49 cit.
6
Astragaloside IV alleviates PM2.5-caused lung toxicity by inhibiting inflammasome‐mediated pyroptosis via NLRP3/caspase-1 axis inhibition in mice
Biomedicine & Pharmacotherapy|2022
44 cit.
7
Salidroside, a phenyl ethanol glycoside from Rhodiola crenulata, orchestrates hypoxic mitochondrial dynamics homeostasis by stimulating Sirt1/p53/Drp1 signaling
Journal of Ethnopharmacology|2022
40 cit.
8
Pretreatment with rosavin attenuates PM2.5‐induced lung injury in rats through antiferroptosis via PI3K/Akt/Nrf2 signaling pathway
Phytotherapy Research|2022
38 cit.
9
Comprehensive Analysis of the Longissimus Dorsi Transcriptome and Metabolome Reveals the Regulatory Mechanism of Different Varieties of Meat Quality
Journal of Agricultural and Food Chemistry|2023
37 cit.
10
Eleutheroside E from pre-treatment of Acanthopanax senticosus (Rupr.etMaxim.) Harms ameliorates high-altitude-induced heart injury by regulating NLRP3 inflammasome-mediated pyroptosis via NLRP3/caspase-1 pathway
International Immunopharmacology|2023
31 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Gregg L. Semenza
Johns Hopkins University
2
Nanduri R. Prabhakar
University of Chicago
3
Paul T. Schumacker
Northwestern University
4
Peter Bärtsch
Heidelberg University
5
Benjamin D. Levine
Texas Health Dallas
6
Randall S. Johnson
Athena Group (United States)
7
Peter A. Robbins
University of Oxford
8
Jun Wang
Wuhan Pulmonary Hospital
9
Johanna Myllyharju
University of Oulu
10
Jean‐Paul Richalet
Association pour la Recherche en Physiologie de l’Environnement

Papers

1
A metagenome-wide association study of gut microbiota in type 2 diabetes
Nature|2012
7k cit.
2
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
Proceedings of the National Academy of Sciences|1995
6.2k cit.
3
SOAPdenovo2: an empirically improved memory-efficient short-read <i>de novo</i> assembler
GigaScience|2012
5.6k cit.
4
ACUTE RESPIRATORY DISTRESS IN ADULTS
The Lancet|1967
4.3k cit.
5
Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1
Molecular and Cellular Biology|1996
4k cit.
6
SOAP2: an improved ultrafast tool for short read alignment
Bioinformatics|2009
3.9k cit.
7
SOAP: short oligonucleotide alignment program
Bioinformatics|2008
3.7k cit.
8
Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life
Cell Host & Microbe|2015
3.4k cit.
9
De novo assembly of human genomes with massively parallel short read sequencing
Genome Research|2009
3k cit.
10
WEGO: a web tool for plotting GO annotations
Nucleic Acids Research|2006
2.8k cit.

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