Leaderboards/Gout, Hyperuricemia, Uric Acid

Gout, Hyperuricemia, Uric Acid

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Arumugam Balasubramanian
Harvard University
2
Yuanyuan Wei
Second Affiliated Hospital of Zhejiang University
3
Inga V. Hochheiser
University of Bonn
4
Huairui Shi
Fudan University
5
Jingxin Xu
Chongqing Medical University
6
Pascal Devant
Boston Children's Hospital
7
Wenchen Yu
Harbin Institute of Technology
8
Xiaohai Zhou
Sinopec (China)
9
Ramzi Vareldzis
Louisiana State University Health Sciences Center New Orleans
10
Tingfen Han
Wenzhou Medical University

Papers

1
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis
Science Immunology|2024
177 cit.
2
Hyperuricemia: An Intriguing Connection to Metabolic Syndrome, Diabetes, Kidney Disease, and Hypertension
Current Hypertension Reports|2024
76 cit.
3
Insights into reproduction-regulating NOD-like receptors
Nature Structural & Molecular Biology|2024
3 cit.
4
Publication in The Journal of Immunology (2025) [W4416451254]
The Journal of Immunology|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Xing Liu
Chinese Academy of Sciences
2
Huabin He
Jiujiang First People's Hospital
3
Dmitry Ratner
VA Boston Healthcare System
4
Kristian K. Starheim
Norwegian University of Science and Technology
5
Zhixing He
Zhejiang Chinese Medical University
6
Zhaofang Bai
Fujian University of Traditional Chinese Medicine
7
Jixi Li
Fudan University
8
Theodore Waller
Ohio Heart & Vascular Center
9
Ting Wu
Huazhong Agricultural University
10
Tetsuo Ohashi
Kyoto University

Papers

1
Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis
Nature|2022
361 cit.
2
Two-Sample Mendelian Randomization Analysis Investigates Causal Associations Between Gut Microbial Genera and Inflammatory Bowel Disease, and Specificity Causal Associations in Ulcerative Colitis or Crohn’s Disease
Frontiers in Immunology|2022
166 cit.
3
Disulfiram blocks inflammatory TLR4 signaling by targeting MD-2
Proceedings of the National Academy of Sciences|2023
59 cit.
4
MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson’s disease
Molecular Neurodegeneration|2023
47 cit.
5
Gut microbiota mediated the toxicity of high concentration of dietary nitrite in C57BL/6 mice
Ecotoxicology and Environmental Safety|2022
44 cit.
6
Insoluble Fiber in Barley Leaf Attenuates Hyperuricemic Nephropathy by Modulating Gut Microbiota and Short-Chain Fatty Acids
Foods|2022
40 cit.
7
Transcription factor Sp1 transcriptionally enhances GSDME expression for pyroptosis
Cell Death and Disease|2024
39 cit.
8
Systematic Analysis of Chemokines Reveals CCL18 is a Prognostic Biomarker in Glioblastoma
Journal of Inflammation Research|2022
26 cit.
9
ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction
Cell Death and Disease|2024
25 cit.
10
Pan-cancer analysis identifies RNA helicase DDX1 as a prognostic marker
Phenomics|2022
23 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Richard J. Johnson
University of Colorado Anschutz Medical Campus
2
Hyon K. Choi
Massachusetts General Hospital
3
Gary C. Curhan
Brigham and Women's Hospital
4
Gabriel Núñez
Michigan Center for Translational Pathology
5
Vishva M. Dixit
Molecular Oncology (United States)
6
Nicola Dalbeth
University of Auckland
7
Robert Terkeltaub
University of California San Diego
8
Michael Doherty
University of Nottingham
9
Nancy Joseph‐Ridge
Deerfield (United States)
10
Tuhina Neogi
Boston University

Papers

1
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nature|2015
3.7k cit.
2
FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex
Cell|1996
3.1k cit.
3
Cryopyrin activates the inflammasome in response to toxins and ATP
Nature|2006
3k cit.
4
Non-canonical inflammasome activation targets caspase-11
Nature|2011
2.5k cit.
5
FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis
Cell|1995
2.4k cit.
6
Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
Cell|1995
2.4k cit.
7
Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt
Science|1997
2.2k cit.
8
K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
Immunity|2013
2.1k cit.
9
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
Nature|2004
1.8k cit.
10
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
Nature|2004
1.8k cit.

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