Leaderboards/Glycosylation and Glycoproteins Research

Glycosylation and Glycoproteins Research

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

Jeffrey A. Ruffolo

Joint BioEnergy Institute

Joakim Nøddeskov Clifford

Technical University of Denmark

Kevin W. Ng

The Francis Crick Institute

Qingzhu Shi

Beijing Institute of Education

Ieva Bagdonaite

University of Copenhagen

Jung-Eun Shin

Harvard University

Cassie R. Bakshani

MicroBio Engineering (United States)

Kelly Boelaars

Amsterdam University Medical Centers

Michal A. Stanczak

Bloomberg (United States)

Gabriel Studer

SIB Swiss Institute of Bioinformatics

Papers

Designing proteins with language models

Nature Biotechnology|2024

97 cit.

Design of highly functional genome editors by modelling CRISPR–Cas sequences

Nature|2025

72 cit.

Publication in Communications Biology (2024) [58 citations, W4394601230]

Communications Biology|2024

58 cit.

Publication in Nature Microbiology (2025) [58 citations, W4407040120]

Nature Microbiology|2025

58 cit.

AbEpiTope-1.0: Improved antibody target prediction by use of AlphaFold and inverse folding

Science Advances|2025

15 cit.

Targeting host O-linked glycan biosynthesis affects Ebola virus replication efficiency and reveals differential GalNAc-T acceptor site preferences on the Ebola virus glycoprotein

Journal of Virology|2024

5 cit.

A fully automated benchmarking suite to compare macromolecular complexes

Nature Methods|2025

3 cit.

Publication in Trends in Immunology (2024) [2 citations, W4404557874]

Trends in Immunology|2024

2 cit.

Publication in Royal Society Open Science (2025) [1 citation, W4413778582]

Royal Society Open Science|2025

1 cit.

What does a language model know about proteins?

Nature Methods|2025

1 cit.

Emerging Leaders

Drafting the new consensus

Papers

Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade

Science Translational Medicine|2022

231 cit.

Data-driven regularization lowers the size barrier of cryo-EM structure determination

Nature Methods|2024

205 cit.

Siglec Receptors Modulate Dendritic Cell Activation and Antigen Presentation to T Cells in Cancer

Frontiers in Cell and Developmental Biology|2022

52 cit.

Facile Synthesis of Sugar Nucleotides from Common Sugars by the Cascade Conversion Strategy

Journal of the American Chemical Society|2022

45 cit.

Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket

Nature Communications|2023

43 cit.

Total synthesis ofLentinus giganteusglycans with antitumor activitiesviastereoselective α-glycosylation and orthogonal one-pot glycosylation strategies

Chemical Science|2022

36 cit.

Heterogeneous MXene Hybrid-Oriented Exosome Isolation and Metabolic Profiling for Early Screening, Subtyping and Follow-up Evaluation of Bladder Cancer

ACS Nano|2023

35 cit.

In Vitro Diagnostic Examination and Prognosis Surveillance by Hierarchical Heterojunction-Assisted Metabolic Analysis

Analytical Chemistry|2022

32 cit.

One-Pot Assembly of Mannose-Capped Lipoarabinomannan Motifs up to 101-Mer from the Mycobacterium tuberculosis Cell Wall

Journal of the American Chemical Society|2024

32 cit.

Highly stereoselective α-glycosylation with GalN 3 donors enabled collective synthesis of mucin-related tumor associated carbohydrate antigens

Chemical Science|2024

32 cit.

Current Senior Leaders

Wrote the book, still writing it

Papers

Comparative Protein Modelling by Satisfaction of Spatial Restraints

Journal of Molecular Biology|1993

13.2k cit.

The carbohydrate-active enzymes database (CAZy) in 2013

Nucleic Acids Research|2013

6.5k cit.

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

Nucleic Acids Research|2008

6k cit.

A classification of glycosyl hydrolases based on amino acid sequence similarities

Biochemical Journal|1991

3.2k cit.

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

Angewandte Chemie International Edition|2009

3.1k cit.

A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems

Journal of the American Chemical Society|2004

2.9k cit.

Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets

Nature Medicine|2000

2.7k cit.

Cell Surface Engineering by a Modified Staudinger Reaction

Science|2000

2.4k cit.

New families in the classification of glycosyl hydrolases based on amino acid sequence similarities

Biochemical Journal|1993

2k cit.

Copper-free click chemistry for dynamic in vivo imaging

Proceedings of the National Academy of Sciences|2007

1.8k cit.

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