Leaderboards/Genomics and Chromatin Dynamics

Genomics and Chromatin Dynamics

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Jaime A. Castro-Mondragón
Inserm
2
Carmen Bravo González‐Blas
VIB-KU Leuven Center for Brain & Disease Research
3
Zhaonan Zou
Kumamoto University
4
Heankel Lyons
The University of Texas Southwestern Medical Center
5
Yanrong Ji
Zhongshan People's Hospital
6
Di Zhang
University of Yamanashi
7
Fayrouz Hammal
Inserm
8
Constantin Ahlmann-Eltze
University College London
9
Wen‐Kang Shen
Sichuan University
10
Ozgur Oksuz
NYU Langone Health

Papers

1
ChIP-Atlas 3.0: a data-mining suite to explore chromosome architecture together with large-scale regulome data
Nucleic Acids Research|2024
185 cit.
2
Publication in Nature Methods (2025) [95 citations, W4412929241]
Nature Methods|2025
95 cit.
3
Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation
Nature Cell Biology|2024
75 cit.
4
Publication in Nature (2025) [28 citations, W4415929055]
Nature|2025
28 cit.
5
Publication in Cell (2025) [21 citations, W4409801542]
Cell|2025
21 cit.
6
Publication in Nature Genetics (2025) [11 citations, W4406036487]
Nature Genetics|2025
11 cit.
7
An automatic annotation tool and reference database for T cell subtypes and states at single-cell resolution
Science Bulletin|2025
8 cit.
8
Publication in RNA (2026) [1 citation, W7119551770]
RNA|2026
1 cit.
9
Publication in Mobile DNA (2025) [W4417042329]
Mobile DNA|2025
0 cit.
10
ChIP-Atlas 2025 update: 10-year anniversary of a data-mining platform for exploring epigenomic landscape
Nucleic Acids Research|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Anthony Mathelier
Oslo University Hospital
2
Wei Xie
IE University
3
Alessandra Dall’Agnese
Whitehead Institute for Biomedical Research
4
Feng Yue
The University of Sydney
5
Erin Curley
Christiana Care Health System
6
J Engreitz
Broad Institute
7
Jennifer E. Phillips‐Cremins
Bioengineering Center
8
David R. Kelley
ISCO International (United States)
9
Elzo de Wit
The Netherlands Cancer Institute
10
Darren A. Cusanovich
University of Arizona

Papers

1
JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
Nucleic Acids Research|2023
1k cit.
2
Subtype-specific 3D genome alteration in acute myeloid leukaemia
Nature|2022
213 cit.
3
Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development
Nature Cell Biology|2022
193 cit.
4
Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation
Science|2022
184 cit.
5
Predicting RNA-seq coverage from DNA sequence as a unifying model of gene regulation
Nature Genetics|2025
170 cit.
6
Compatibility rules of human enhancer and promoter sequences
Nature|2022
167 cit.
7
scBasset: sequence-based modeling of single-cell ATAC-seq using convolutional neural networks
Nature Methods|2022
152 cit.
8
EagleC: A deep-learning framework for detecting a full range of structural variations from bulk and single-cell contact maps
Science Advances|2022
151 cit.
9
OBOX regulates mouse zygotic genome activation and early development
Nature|2023
142 cit.
10
Cohesin-mediated loop anchors confine the locations of human replication origins
Nature|2022
127 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Richard A. Young
Whitehead Institute for Biomedical Research
2
Eric S. Lander
Broad Institute
3
Bing Ren
University of California San Diego
4
C. David Allis
Rockefeller University
5
Robert Tjian
University of California, Berkeley
6
Job Dekker
Howard Hughes Medical Institute
7
X. Shirley Liu
Harbin Medical University
8
William Stafford Noble
University of Washington
9
David Botstein
Massachusetts Institute of Technology
10
R Waterston
University of Washington

Papers

1
Model-based Analysis of ChIP-Seq (MACS)
Genome biology|2008
19.9k cit.
2
Cluster analysis and display of genome-wide expression patterns
Proceedings of the National Academy of Sciences|1998
16.4k cit.
3
Molecular portraits of human breast tumours
Nature|2000
16.3k cit.
4
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
Science|1999
11.6k cit.
5
MEME SUITE: tools for motif discovery and searching
Nucleic Acids Research|2009
11.5k cit.
6
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
Science|2009
9.6k cit.
7
The language of covalent histone modifications
Nature|2000
8.6k cit.
8
Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
PubMed|1980
8.4k cit.
9
Topological domains in mammalian genomes identified by analysis of chromatin interactions
Nature|2012
7.4k cit.
10
MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations
Genomics|1987
6.7k cit.

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