Leaderboards/Genetic factors in colorectal cancer

Genetic factors in colorectal cancer

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Bastien Nguyen
Eli Lilly (United States)
2
Marcos Díaz‐Gay
University of California San Diego
3
Ignasius Joanito
SciGenom Labs (India)
4
Winston R. Becker
Stanford University
5
Jens Luebeck
University of Washington Tacoma
6
Fadl A. Zeineddine
Methodist Hospital
7
Doruk Beyter
deCODE Genetics (Iceland)
8
P.G.M. de Gooyer
The Netherlands Cancer Institute
9
Simone Rubinacci
Broad Institute
10
Steven Laurie
Centro Nacional de Análisis Genómico

Papers

1
Geographic and age variations in mutational processes in colorectal cancer
Nature|2025
123 cit.
2
Neoadjuvant nivolumab and relatlimab in locally advanced MMR-deficient colon cancer: a phase 2 trial
Nature Medicine|2024
102 cit.
3
Publication in Nature Medicine (2025) [43 citations, W4406537089]
Nature Medicine|2025
43 cit.
4
The mutagenic forces shaping the genomes of lung cancer in never smokers
Nature|2025
37 cit.
5
247P Radiotherapy (RT), atezolizumab (atezo) and bevacizumab (bev) to increase organ preservation in rectal cancer: The TARZAN study
Annals of Oncology|2024
8 cit.
6
503O Neoadjuvant nivolumab (nivo) plus relatlimab (rela) in MMR-deficient colon cancer: Results of the NICHE-3 study
Annals of Oncology|2024
4 cit.
7
Publication in Cancer Research (2024) [1 citation, W4393988254]
Cancer Research|2024
1 cit.
8
Publication in Cancer Genetics (2024) [1 citation, W4402866983]
Cancer Genetics|2024
1 cit.
9
Publication in Journal of Hepatology (2024) [W4399459527]
Journal of Hepatology|2024
0 cit.
10
Delineating histomorphological signatures of iCMS subtypes in colorectal cancer using multiplexed fluorescence-in-situ hybridization.
Journal of Clinical Oncology|2024
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Hao Wang
University of Electronic Science and Technology of China
2
Jennifer N. Durham
Sidney Kimmel Comprehensive Cancer Center
3
Bjarne R. Bartlett
State University of New York
4
Kellie N. Smith
Bloomberg (United States)
5
Peter J. Campbell
Wellcome Sanger Institute
6
Lincoln D. Stein
Ontario Institute for Cancer Research
7
Andrea Sottoriva
Institute of Cancer Research
8
Lisa A. Gurski
National Comprehensive Cancer Network
9
Ruben van Boxtel
Oncode Institute
10
Ina Felau
National Cancer Institute

Papers

1
Rectal Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology
Journal of the National Comprehensive Cancer Network|2022
819 cit.
2
NCCN Guidelines® Insights: Bladder Cancer, Version 2.2022
Journal of the National Comprehensive Cancer Network|2022
302 cit.
3
Bladder Cancer, Version 3.2024
Journal of the National Comprehensive Cancer Network|2024
236 cit.
4
NCCN Guidelines® Insights: Rectal Cancer, Version 3.2024
Journal of the National Comprehensive Cancer Network|2024
215 cit.
5
MutationalPatterns: the one stop shop for the analysis of mutational processes
BMC Genomics|2022
181 cit.
6
NCCN Guidelines® Insights: Kidney Cancer, Version 2.2024
Journal of the National Comprehensive Cancer Network|2024
166 cit.
7
The co-evolution of the genome and epigenome in colorectal cancer
Nature|2022
125 cit.
8
Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer
Cancer Cell|2024
89 cit.
9
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors
Nature Genetics|2023
79 cit.
10
Lung tumor–infiltrating T<sub>reg</sub>have divergent transcriptional profiles and function linked to checkpoint blockade response
Science Immunology|2023
74 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Bert Vogelstein
Johns Hopkins University
2
Luis A. Díaz
Memorial Sloan Kettering Cancer Center
3
Donald Maxwell Parkin
University of Oxford
4
Gad Getz
Broad Institute
5
Kenneth W. Kinzler
Johns Hopkins University
6
Michael R. Stratton
Wellcome Sanger Institute
7
Joshua M. Stuart
University of California, Santa Cruz
8
Victor E. Velculescu
Johns Hopkins University
9
Richard D. Kolodner
Ludwig Cancer Research
10
Ahmedin Jemal
American Cancer Society

Papers

1
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
CA A Cancer Journal for Clinicians|2018
87.7k cit.
2
Global cancer statistics
CA A Cancer Journal for Clinicians|2011
55k cit.
3
Global cancer statistics, 2012
CA A Cancer Journal for Clinicians|2015
27.4k cit.
4
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Analytical Biochemistry|1983
25.2k cit.
5
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
CA A Cancer Journal for Clinicians|2024
23.1k cit.
6
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
International Journal of Cancer|2010
21.4k cit.
7
Cancer statistics, 2020
CA A Cancer Journal for Clinicians|2020
21.4k cit.
8
Cancer statistics, 2019
CA A Cancer Journal for Clinicians|2019
21k cit.
9
Global Cancer Statistics, 2002
CA A Cancer Journal for Clinicians|2005
18.4k cit.
10
Cancer statistics, 2022
CA A Cancer Journal for Clinicians|2022
18.2k cit.

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