Leaderboards/Epigenetics and DNA Methylation

Epigenetics and DNA Methylation

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Elliot Sollis
European Bioinformatics Institute
2
Jacob T. Nearing
Broad Institute
3
Netanel Loyfer
Hebrew University of Jerusalem
4
Zhaonan Zou
Kumamoto University
5
Bastien Nguyen
Eli Lilly (United States)
6
Di Zhang
University of Yamanashi
7
Jia-Jian Loh
University of Hong Kong
8
Pranavi Koppula
The University of Texas MD Anderson Cancer Center
9
Laura C. Hinte
ETH Zurich
10
Yuelong Yan
The University of Texas MD Anderson Cancer Center

Papers

1
Hallmarks of cancer stemness
Cell stem cell|2024
259 cit.
2
Publication in Nature (2024) [219 citations, W4404467861]
Nature|2024
219 cit.
3
ChIP-Atlas 3.0: a data-mining suite to explore chromosome architecture together with large-scale regulome data
Nucleic Acids Research|2024
185 cit.
4
Publication in Nature (2025) [28 citations, W4415929055]
Nature|2025
28 cit.
5
GPR56: GPCR as a guardian against ferroptosis
Cell Metabolism|2024
4 cit.
6
Publication in Molecular Metabolism (2025) [2 citations, W4411927873]
Molecular Metabolism|2025
2 cit.
7
Capturing sequence ambiguity among taxa in a primer-specific manner to improve taxonomic classification of amplicon sequencing
Nucleic Acids Research|2025
2 cit.
8
<i>wgbstools</i> : a computational suite for DNA methylation sequencing data analysis
Life Science Alliance|2026
2 cit.
9
Dodging death
Nature Chemical Biology|2024
0 cit.
10
Referee report. For: Computational Study Protocol: Leveraging Synthetic Data to Validate a Benchmark Study for Differential Abundance Tests for 16S Microbiome Sequencing Data [version 1; peer review: 2 approved with reservations]
Faculty of 1000 Research Ltd|2024
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
David Mallery
Translational Genomics Research Institute
2
Wei Xie
IE University
3
John A. Demchok
National Cancer Institute
4
Ina Felau
National Cancer Institute
5
Natália D. Aredes
Universidade Federal de Goiás
6
Michelle Bellair
Lunar and Planetary Institute
7
Moriah G. Nissan
Van Andel Institute
8
Laxmi Lolla
Windber Research Institute
9
Donghui Tan
Jiangxi College of Applied Technology
10
Ruben van Boxtel
Oncode Institute

Papers

1
Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development
Nature Cell Biology|2022
193 cit.
2
Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation
Science|2022
184 cit.
3
MutationalPatterns: the one stop shop for the analysis of mutational processes
BMC Genomics|2022
181 cit.
4
OBOX regulates mouse zygotic genome activation and early development
Nature|2023
142 cit.
5
Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer
Cancer Cell|2024
89 cit.
6
Encapsulation of Platinum Prodrugs into PC7A Polymeric Nanoparticles Combined with Immune Checkpoint Inhibitors for Therapeutically Enhanced Multimodal Chemotherapy and Immunotherapy by Activation of the STING Pathway
Advanced Science|2022
61 cit.
7
NR5A2 connects zygotic genome activation to the first lineage segregation in totipotent embryos
Cell Research|2023
53 cit.
8
Mapping putative enhancers in mouse oocytes and early embryos reveals TCF3/12 as key folliculogenesis regulators
Nature Cell Biology|2024
47 cit.
9
Multifaceted SOX2-chromatin interaction underpins pluripotency progression in early embryos
Science|2023
44 cit.
10
Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos
Nature Structural & Molecular Biology|2024
43 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Yi Zhang
Sun Yat-sen University
2
Rudolf Jaenisch
Whitehead Institute for Biomedical Research
3
Wei Li
Harbin Medical University
4
X. Shirley Liu
Harbin Medical University
5
Adrian Bird
Princip (Czechia)
6
Stephen B. Baylin
Johns Hopkins University
7
C. David Allis
Rockefeller University
8
Andrew P. Feinberg
Johns Hopkins University
9
Jun Wang
Wuhan Pulmonary Hospital
10
Manel Esteller
Institució Catalana de Recerca i Estudis Avançats

Papers

1
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Analytical Biochemistry|1983
25.2k cit.
2
Model-based Analysis of ChIP-Seq (MACS)
Genome biology|2008
19.9k cit.
3
The language of covalent histone modifications
Nature|2000
8.6k cit.
4
A metagenome-wide association study of gut microbiota in type 2 diabetes
Nature|2012
7k cit.
5
TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells
Cancer Research|2017
6.6k cit.
6
TIMER2.0 for analysis of tumor-infiltrating immune cells
Nucleic Acids Research|2020
5.7k cit.
7
SOAPdenovo2: an empirically improved memory-efficient short-read <i>de novo</i> assembler
GigaScience|2012
5.6k cit.
8
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
Nature Medicine|2018
5.6k cit.
9
Histone H3K27ac separates active from poised enhancers and predicts developmental state
Proceedings of the National Academy of Sciences|2010
4.5k cit.
10
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
Cell|1992
4k cit.

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