Leaderboards/DNA and Nucleic Acid Chemistry

DNA and Nucleic Acid Chemistry

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Obtin Alkhamis
North Carolina State University
2
Joana Figueiredo
University of Beira Interior
3
Isabel Esain-Garcia
Howard Hughes Medical Institute
4
Thumpati Prasanth
Virginia Commonwealth University
5
Prakash Kharel
Harvard University
6
Scarlett J. Barker
Denali Therapeutics (United States)
7
Yuzhe Ding
University of Waterloo
8
Jochen Spiegel
Cancer Research UK Cambridge Center
9
Ren-Xuan Wang
Hunan University
10
Honorine Lardeux
University of Geneva

Papers

1
G-quadruplex ligands in cancer therapy: Progress, challenges, and clinical perspectives
Life Sciences|2024
135 cit.
2
G-quadruplex DNA structure is a positive regulator of <i>MYC</i> transcription
Proceedings of the National Academy of Sciences|2024
135 cit.
3
Publication in Science Translational Medicine (2024) [119 citations, W4401596729]
Science Translational Medicine|2024
119 cit.
4
Recent advances and current challenges in hydrophilic interaction chromatography for the analysis of therapeutic oligonucleotides
TrAC Trends in Analytical Chemistry|2024
60 cit.
5
High-Affinity Aptamers for<i>In Vitro</i>and<i>In Vivo</i>Cocaine Sensing
Journal of the American Chemical Society|2024
59 cit.
6
Unravelling the Link between Oligonucleotide Structure and Diastereomer Separation in Hydrophilic Interaction Chromatography
Analytical Chemistry|2024
43 cit.
7
Publication in Chinese Journal of Chemistry (2024) [30 citations, W4399133749]
Chinese Journal of Chemistry|2024
30 cit.
8
Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity
Nucleic Acids Research|2025
27 cit.
9
Publication in ACS Chemical Biology (2024) [22 citations, W4391035923]
ACS Chemical Biology|2024
22 cit.
10
Nuclease-assisted selection of slow-off rate aptamers
Science Advances|2024
20 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
S. Bisht
European Molecular Biology Laboratory
2
Indra A. Shaltiël
Heidelberg University
3
Jukka Kallijärvi
University of Helsinki
4
Chun Kit Kwok
City University of Hong Kong
5
Nicole A. Leal
Foundation for Applied Molecular Evolution
6
Aleksandr B. Sahakyan
University of Oxford
7
Silvie Foldynová-Trantírková
Central European Institute of Technology
8
Petr Šulc
Arizona State University
9
Bret Freudenthal
The University of Kansas Cancer Center
10
Daryl W. Yee
École Polytechnique Fédérale de Lausanne

Papers

1
A hold-and-feed mechanism drives directional DNA loop extrusion by condensin
Science|2022
123 cit.
2
Inverse design of a pyrochlore lattice of DNA origami through model-driven experiments
Science|2024
85 cit.
3
Structural basis for APE1 processing DNA damage in the nucleosome
Nature Communications|2022
68 cit.
4
Designing the Self-Assembly of Arbitrary Shapes Using Minimal Complexity Building Blocks
ACS Nano|2023
38 cit.
5
Generative and interpretable machine learning for aptamer design and analysis of in vitro sequence selection
PLoS Computational Biology|2022
36 cit.
6
Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics
Nucleic Acids Research|2023
32 cit.
7
SAT-assembly: a new approach for designing self-assembling systems
Journal of Physics Condensed Matter|2022
30 cit.
8
An RNA G‐Quadruplex Structure within the ADAR 5′UTR Interacts with DHX36 Helicase to Regulate Translation
Angewandte Chemie International Edition|2022
30 cit.
9
Reversible Diffusionless Phase Transitions in 3D Nanoparticle Superlattices
Journal of the American Chemical Society|2023
28 cit.
10
Selective targeting of parallel G-quadruplex structure using L-RNA aptamer
Nucleic Acids Research|2023
27 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Peter A. Kollman
Rutgers, The State University of New Jersey
2
Jacqueline K. Barton
California Institute of Technology
3
David A. Case
Rutgers Sexual and Reproductive Health and Rights
4
Bert Vogelstein
Johns Hopkins University
5
William J. Rutter
U.S. Vegetable Laboratory
6
Shankar Balasubramanian
Massachusetts Institute of Technology
7
Nadrian C. Seeman
New York University
8
Stephen Neidle
University College London
9
Itamar Willner
Hebrew University of Jerusalem
10
Dinshaw J. Patel
Memorial Sloan Kettering Cancer Center

Papers

1
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Analytical Biochemistry|1983
25.2k cit.
2
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Biochemistry|1979
22.2k cit.
3
Development and testing of a general amber force field
Journal of Computational Chemistry|2004
19.6k cit.
4
A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules
Journal of the American Chemical Society|1995
13.1k cit.
5
The Amber biomolecular simulation programs
Journal of Computational Chemistry|2005
9.6k cit.
6
A well-behaved electrostatic potential based method using charge restraints for deriving atomic charges: the RESP model
The Journal of Physical Chemistry|1993
8.1k cit.
7
Settle: An analytical version of the SHAKE and RATTLE algorithm for rigid water models
Journal of Computational Chemistry|1992
7.6k cit.
8
THE weighted histogram analysis method for free‐energy calculations on biomolecules. I. The method
Journal of Computational Chemistry|1992
6.9k cit.
9
Genetic Alterations during Colorectal-Tumor Development
New England Journal of Medicine|1988
6.8k cit.
10
Surfing the p53 network
Nature|2000
6.6k cit.

Reagents for DNA and Nucleic Acid Chemistry

Citation-validated products used in this field

🔥 Trending

Gaining adoption fast

⭐ Top Rated

Best all-around

MilliporeEvidence 65

Anti-DNA, single stranded, clone 16-19

Cited in 7 papers
#MAB3034
View Evidence →
Cell Signaling TechnologyEvidence 66

Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit Monoclonal Antibody (Alexa Fluor® 594 Conjugate)

Cited in 7 papers
#10584$493
View Evidence →
New England Biolabs

Gel Loading Dye, Purple (6X)

Cited in 7 papers
#B7024S
View Evidence →

🌟 All-Time

Most validated

Cell Signaling TechnologyEvidence 65

Phospho-Histone H3 (Ser10) (D7N8E) Rabbit Monoclonal Antibody (BSA and Azide Free)

Cited in 18 papers
#47398$898
View Evidence →
Cell Signaling TechnologyEvidence 65

Acetyl-alpha-Tubulin (Lys40) (D20G3) Rabbit Monoclonal Antibody (SignalFlex™ mFluor™ Violet 510 Conjugate)

Cited in 10 papers
#23635$486
View Evidence →
Cell Signaling TechnologyEvidence 65

RRM1 (D12F12) Rabbit Monoclonal Antibody

Cited in 8 papers
#8637$161,384
View Evidence →