Leaderboards/Cytokine Signaling Pathways and Interactions

Cytokine Signaling Pathways and Interactions

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Caleb R. Glassman
Stanford University
2
Xiu-Ming Li
Soochow University
3
Bikash Mishra
Hospital for Special Surgery
4
Irem Ozel
University of Duisburg-Essen
5
Emma Guilbaud
Fox Chase Cancer Center
6
Johann S. Bergholz
Broad Institute
7
Robert A. Saxton
Stanford University
8
Ipsita Subudhi
NYU Langone Health
9
Rui Zhang
Capital Medical University
10
Cayce Dorrier
University of California San Diego

Papers

1
Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
Cell Reports|2024
105 cit.
2
Publication in Immunity (2024) [83 citations, W4398146780]
Immunity|2024
83 cit.
3
Publication in Nature Communications (2024) [33 citations, W4394988890]
Nature Communications|2024
33 cit.
4
Publication in Cell Death and Disease (2024) [6 citations, W4400279697]
Cell Death and Disease|2024
6 cit.
5
Publication in Signal Transduction and Targeted Therapy (2025) [1 citation, W4409657493]
Signal Transduction and Targeted Therapy|2025
1 cit.
6
Abstract LB117: Virus-inspired Particles (ViPs) harnessing cytomegalovirus immune memory for local and systemic cancer immunotherapy
Cancer Research|2024
0 cit.
7
Publication in Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2024) [W4402781006]
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease|2024
0 cit.
8
Publication in Experimental Eye Research (2025) [W4415313387]
Experimental Eye Research|2025
0 cit.
9
Publication in Regular and Young Investigator Award Abstracts (2025) [W4415900381]
Regular and Young Investigator Award Abstracts|2025
0 cit.
10
Publication in Cancer Research (2026) [W7148924588]
Cancer Research|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Géraldine Farjot
Air Liquide (France)
2
Leonie Unterholzner
Lancaster University
3
Nadia J. Kershaw
The University of Melbourne
4
Manuel Valiente
Instituto de Filosofía
5
Dina M. Bitar
The Ohio State University
6
James P. Pirruccello
University of California, San Francisco
7
Yasushi Kondo
Paul Scherrer Institute
8
Saul J. Priceman
University of Southern California
9
Jin Fan
Jiangsu Province Hospital
10
Zexian Fu
Hebei University of Engineering

Papers

1
PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophages
Journal for ImmunoTherapy of Cancer|2022
117 cit.
2
PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer: a phase 1 trial
Nature Medicine|2024
116 cit.
3
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting
Nature Communications|2023
102 cit.
4
Genetic analysis of right heart structure and function in 40,000 people
Nature Genetics|2022
98 cit.
5
Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism
Nature Medicine|2022
82 cit.
6
TIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells
Cancer Discovery|2024
40 cit.
7
Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits
Cancer Cell|2023
36 cit.
8
The Genetic Determinants of Aortic Distention
Journal of the American College of Cardiology|2023
35 cit.
9
Deep learning of left atrial structure and function provides link to atrial fibrillation risk
Nature Communications|2024
35 cit.
10
Solid tumour CAR-T cells engineered with fusion proteins targeting PD-L1 for localized IL-12 delivery
Nature Biomedical Engineering|2025
30 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Michael Karin
Discovery Institute
2
Shizuo Akira
Kunsan National University
3
Tadamitsu Kishimoto
The University of Osaka
4
Tadatsugu Taniguchi
The University of Tokyo
5
Hua Yu
City Of Hope National Medical Center
6
Richard A. Flavell
Yale University
7
George R. Stark
The Honourable Society of Lincoln's Inn
8
Robert D. Schreiber
Parker Institute for Cancer Immunotherapy
9
David E. Levy
New York University
10
Ruslan Medzhitov
Howard Hughes Medical Institute

Papers

1
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
Nature|2001
6.1k cit.
2
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
Nature|1997
5.5k cit.
3
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
Cell|2004
4.2k cit.
4
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
Nature|2006
3.8k cit.
5
Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the <i>Lps</i> Gene Product
The Journal of Immunology|1999
3.4k cit.
6
Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components
Immunity|1999
3.4k cit.
7
Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.
Proceedings of the National Academy of Sciences|1979
3.4k cit.
8
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
Science|2003
3.2k cit.
9
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
Cell|1987
3k cit.
10
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
Nature|2014
2.9k cit.

Reagents for Cytokine Signaling Pathways and Interactions

Citation-validated products used in this field

🔥 Trending

Gaining adoption fast

⭐ Top Rated

Best all-around

Cell Signaling Technology

Phospho-VEGF Receptor 2 (Tyr996) Antibody

Cited in 28 papers
#2474$148,362
View Evidence →
Thermo Fisher ScientificEvidence 69

JAK2 Recombinant Rabbit Monoclonal Antibody

Cited in 25 papers
#RAB02515
View Evidence →
Thermo Fisher ScientificEvidence 69

JAK2 Recombinant Rabbit Monoclonal Antibody

Cited in 25 papers
#RAB01251
View Evidence →

🌟 All-Time

Most validated

Santa Cruz Biotechnology

Anti-p-Stat3 Antibody (B-7)

Cited in 31 papers
#sc-8059
View Evidence →
Cell Signaling TechnologyEvidence 63

CoREST (F4R4K) Rabbit Monoclonal Antibody

Cited in 30 papers
#20059$161,376
View Evidence →
Santa Cruz Biotechnology

Stat3 (C-20)

Cited in 30 papers
#sc-482
View Evidence →