Leaderboards/CRISPR Screens

CRISPR Screens

Last updated May 19, 2026

Rising Stars

New and hot

Rising Stars Researchers

1
Yuqi Wang
Westlake University
441 cit.
2
Xiufeng Li
Peking University
237 cit.
3
Calvin Law
Northwestern University
234 cit.
4
Christine Y. Yeh
Stanford University
195 cit.
5
Xinhe Zheng
Scripps Health
189 cit.
6
Wen-Wei Liang
New York Genome Center
174 cit.
7
Tyson J. Ruetz
Stanford University
174 cit.
8
Yu Hou
Brigham and Women's Hospital
174 cit.
9
Justin L. Engel
The University of Texas Southwestern Medical Center
162 cit.
10
Costanza Borrelli
ETH Zurich
159 cit.

Rising Stars Papers

1
ACSL4 and polyunsaturated lipids support metastatic extravasation and colonization
Cell|2024
146 cit.
2
LINE-1 transcription activates long-range gene expression
Nature Genetics|2024
78 cit.
3
Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus
Nature|2024
77 cit.
4
Mapping spatial organization and genetic cell-state regulators to target immune evasion in ovarian cancer
Nature Immunology|2024
64 cit.
5
Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development
Cell|2024
62 cit.
6
RETRACTED: Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells
Cell|2024
57 cit.
7
CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells
Nature|2024
57 cit.
8
Neuropeptide signalling orchestrates T cell differentiation
Nature|2024
57 cit.
9
The Fanconi anemia pathway induces chromothripsis and ecDNA-driven cancer drug resistance
Cell|2024
53 cit.
10
In vivo interaction screening reveals liver-derived constraints to metastasis
Nature|2024
52 cit.

Rising Stars Reagents

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Emerging Leaders

Gaining momentum

Emerging Leaders Researchers

1
Britt Adamson
Princeton University
309 cit.
2
Deng Pan
Center for Life Sciences
254 cit.
3
Jennifer A. Doudna
QB3
183 cit.
4
Jun Wang
New York University
181 cit.
5
Alexander Marson
Gladstone Institutes
179 cit.
6
Min Luo
Ministry of Science and Technology
174 cit.
7
Hongbo Chi
St. Jude Children's Research Hospital
152 cit.
8
Israel Cañadas
Fox Chase Cancer Center
146 cit.
9
Artemis G. Hatzigeorgiou
University of Thessaly
136 cit.
10
Mathew J. Garnett
Wellcome Sanger Institute
131 cit.

Emerging Leaders Papers

1
Improving prime editing with an endogenous small RNA-binding protein
Nature|2024
206 cit.
2
Tumor aerobic glycolysis confers immune evasion through modulating sensitivity to T cell-mediated bystander killing via TNF-α
Cell Metabolism|2023
254 cit.
3
Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells
Cell|2023
183 cit.
4
A membrane-associated MHC-I inhibitory axis for cancer immune evasion
Cell|2023
181 cit.
5
CD300ld on neutrophils is required for tumour-driven immune suppression
Nature|2023
174 cit.
6
Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer
Nature|2023
152 cit.
7
Targeting DHX9 Triggers Tumor-Intrinsic Interferon Response and Replication Stress in Small Cell Lung Cancer
Cancer Discovery|2024
97 cit.
8
DIANA-miRPath v4.0: expanding target-based miRNA functional analysis in cell-type and tissue contexts
Nucleic Acids Research|2023
136 cit.
9
A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization
Cancer Cell|2024
87 cit.
10
RHINO directs MMEJ to repair DNA breaks in mitosis
Science|2023
129 cit.

Emerging Leaders Reagents

Coming soon

All-Time Leaders

The canon

All-Time Leaders Researchers

1
Feng Zhang
Broad Institute
28.5k cit.
2
David E. Root
Broad Institute
19.9k cit.
3
Feng Shao
National Institute of Biological Sciences, Beijing
19.3k cit.
4
Marcus Conrad
Helmholtz Zentrum München
11.9k cit.
5
David M. Sabatini
Massachusetts Institute of Technology
11.6k cit.
6
X. Shirley Liu
Dana-Farber Cancer Institute
11.4k cit.
7
James A. Olzmann
Chan Zuckerberg Initiative (United States)
10.5k cit.
8
Maximilian Haeussler
University of California, Santa Cruz
7.4k cit.
9
Mike Tyers
Mount Sinai Hospital
6.7k cit.
10
Aviad Tsherniak
Broad Institute
6.4k cit.

All-Time Leaders Papers

1
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Nature|2015
6.4k cit.
2
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
Science|2013
5.5k cit.
3
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
Nature Biotechnology|2016
4.9k cit.
4
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
Nature Chemical Biology|2016
4k cit.
5
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
Nature|2019
3.5k cit.
6
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
Nature|2014
2.9k cit.
7
MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens
Genome biology|2014
2.8k cit.
8
CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens
Nucleic Acids Research|2018
2.5k cit.
9
Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
Nature Genetics|2017
2.1k cit.
10
Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
Cell|2016
1.9k cit.

All-Time Leaders Reagents

Coming soon

Indexing CRISPR Screens Reagents

Citation data for reagents in this field is currently compiling.