Leaderboards/Complement system in diseases

Complement system in diseases

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
C. Donado
Brigham and Women's Hospital
2
Mikhail Binnewies
University of California, San Francisco
3
William N. Voss
The University of Texas at Austin
4
Lisa N. Kasiewicz
Eli Lilly (United States)
5
Alexander A. Sousa
Broad Institute
6
Jivin Yu
Korea University
7
Stephanie M. Salabarria
University of Florida
8
Roarke A. Kamber
University of California, San Francisco
9
Marie V. Daugan
Idera Pharmaceuticals (United States)
10
Mariona Estapé Sentí
University Medical Center Utrecht

Papers

1
Granzyme K activates the entire complement cascade
Nature|2025
109 cit.
2
Publication in Frontiers in Molecular Biosciences (2024) [93 citations, W4390541689]
Frontiers in Molecular Biosciences|2024
93 cit.
3
mRNA delivery systems for cancer immunotherapy: Lipid nanoparticles and beyond
Advanced Drug Delivery Reviews|2024
85 cit.
4
Publication in Nature Biomedical Engineering (2024) [52 citations, W4400503129]
Nature Biomedical Engineering|2024
52 cit.
5
Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination
Cell Reports Medicine|2024
32 cit.
6
Publication in Cell (2025) [29 citations, W4412527449]
Cell|2025
29 cit.
7
NANOSPRESSO: toward personalized, locally produced nucleic acid nanomedicines
Frontiers in Science|2025
15 cit.
8
Publication in Journal of Investigative Dermatology (2024) [W4400826166]
Journal of Investigative Dermatology|2024
0 cit.
9
Publication in Frontiers for Young Minds (2025) [W4412683836]
Frontiers for Young Minds|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Guest Editor Joseph Schwartz
Columbia University Irving Medical Center
2
Erin E. West
National Heart Lung and Blood Institute
3
Dominique Tersago
Ghent University
4
Jianmin Ye
South China Normal University
5
Jesse E. Hanson
Gene Therapy Laboratory
6
Jessica R. MacNeil
Centers for Disease Control and Prevention
7
Sarah Scharf
Bernhard Nocht Institute for Tropical Medicine
8
Neta Regev‐Rudzki
Weizmann Institute of Science
9
Simon Trowitzsch
Goethe University Frankfurt
10
Arne Moeller
Osnabrück University

Papers

1
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models
Nature Aging|2022
320 cit.
2
Complement C3 Regulates Inflammatory Response and Monocyte/Macrophage Phagocytosis of Streptococcus agalactiae in a Teleost Fish
International Journal of Molecular Sciences|2022
51 cit.
3
Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection
Immunity|2023
49 cit.
4
Malaria parasites release vesicle subpopulations with signatures of different destinations
EMBO Reports|2022
36 cit.
5
Artificial intelligence–based method for the rapid detection of fish parasites (Ichthyophthirius multifiliis, Gyrodactylus kobayashii, and Argulus japonicus)
Aquaculture|2022
28 cit.
6
Teleost fish IgM+ plasma-like cells possess IgM-secreting, phagocytic, and antigen-presenting capacities
Frontiers in Immunology|2022
27 cit.
7
Structural basis of substrate recognition by human tRNA splicing endonuclease TSEN
Nature Structural & Molecular Biology|2023
27 cit.
8
Structure of the endosomal CORVET tethering complex
Nature Communications|2024
16 cit.
9
The ABC transporter MsbA in a dozen environments
Structure|2025
15 cit.
10
Efficient nitrogen removal by heterotrophic nitrification-aerobic denitrification yeast Candida boidinii L21: Performance, pathway and application
Bioresource Technology|2024
14 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
John D. Lambris
University of Pennsylvania
2
Peter A. Ward
Dorset County Hospital
3
Véronique Frémeaux‐Bacchi
Assistance Publique – Hôpitaux de Paris
4
Giuseppe Remuzzi
Mario Negri Institute for Pharmacological Research
5
B. Paul Morgan
UK Dementia Research Institute
6
Louis H. Miller
National Institute of Allergy and Infectious Diseases
7
Peter Garred
University of Copenhagen
8
Peter F. Zipfel
Systems Analytics (United States)
9
Mohamed R. Daha
University of Groningen
10
Piet Gros
Utrecht University

Papers

1
Immunodesign of experimental sepsis by cecal ligation and puncture
Nature Protocols|2008
2.2k cit.
2
The Resistance Factor to<i>Plasmodium vivax</i>in Blacks
New England Journal of Medicine|1976
1.3k cit.
3
Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions.
PubMed|1982
1.2k cit.
4
Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg
Cell|1993
1.1k cit.
5
Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins
Cell|1986
1k cit.
6
Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype
Clinical Journal of the American Society of Nephrology|2010
1k cit.
7
Switches in expression of plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes
Cell|1995
1k cit.
8
Preventing Microalbuminuria in Type 2 Diabetes
New England Journal of Medicine|2004
1k cit.
9
Adhesion molecules and inflammatory injury
The FASEB Journal|1994
1k cit.
10
Generation of C5a in the absence of C3: a new complement activation pathway
Nature Medicine|2006
974 cit.

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