Leaderboards/Circular RNAs in diseases

Circular RNAs in diseases

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Botai Li
Chinese Academy of Sciences
2
Fernanda G. Kugeratski
The University of Texas MD Anderson Cancer Center
3
Gavin Metcalf
Anglia Ruskin University
4
Ziwen Pan
Shandong University
5
Runjie Song
Zhengzhou University
6
Mengting Niu
University of Science and Technology of China
7
Laura Amaya
Stanford University
8
Shufen Xu
Second Affiliated Hospital of Nanjing Medical University
9
Jian Zhong
Sun Yat-sen University
10
Si-Kun Guo
Center for Excellence in Molecular Cell Science

Papers

1
MicroRNAs: circulating biomarkers for the early detection of imperceptible cancers via biosensor and machine-learning advances
Oncogene|2024
173 cit.
2
Publication in Advanced Materials (2024) [91 citations, W4395068470]
Advanced Materials|2024
91 cit.
3
A computational model of circRNA-associated diseases based on a graph neural network: prediction and case studies for follow-up experimental validation
BMC Biology|2024
28 cit.
4
Publication in Advanced Materials (2024) [20 citations, W4400787364]
Advanced Materials|2024
20 cit.
5
Publication in Molecular Cell (2024) [18 citations, W4397002857]
Molecular Cell|2024
18 cit.
6
Identification, characterization and expression analysis of circRNA encoded by SARS-CoV-1 and SARS-CoV-2
Briefings in Bioinformatics|2024
14 cit.
7
CircRNA identification and feature interpretability analysis
BMC Biology|2024
13 cit.
8
Interpretable multi-instance heterogeneous graph network learning modelling CircRNA-drug sensitivity association prediction
BMC Biology|2025
7 cit.
9
Publication in Molecular Cell (2024) [W4399390625]
Molecular Cell|2024
0 cit.
10
Princesa de Gales e Rei Charles: uma em cada duas pessoas desenvolve câncer durante a vida - as doenças e os tratamentos explicados
Unknown Journal|2024
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Petar Glažar
Vertically Integrated Systems (Germany)
2
Luis R. Hernández-Miranda
Humboldt-Universität zu Berlin
3
Shuying Shen
Sir Run Run Shaw Hospital
4
Fabio Sanna
Churchill Hospital
5
Jun Wang
Peking University
6
Pedro Miura
University of Connecticut
7
Hao Xue
Shandong University
8
Feng‐Wei Wang
Beijing Tongren Hospital
9
Yongxin Zhou
Tongji University
10
Shenglin Huang
South China Agricultural University

Papers

1
CircRREB1 mediates lipid metabolism related senescent phenotypes in chondrocytes through FASN post-translational modifications
Nature Communications|2023
62 cit.
2
The N<sup>6</sup>-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2
Theranostics|2022
57 cit.
3
Molecular mechanisms and clinical implications of the gold drug auranofin
Coordination Chemistry Reviews|2023
48 cit.
4
Oxidative stress-induced circKIF18A downregulation impairs MCM7-mediated anti-senescence in intervertebral disc degeneration
Experimental & Molecular Medicine|2022
47 cit.
5
Mex-3 RNA binding family member A (MEX3A)/circMPP6 complex promotes colorectal cancer progression by inhibiting autophagy
Signal Transduction and Targeted Therapy|2024
39 cit.
6
Coordination of alternative splicing and alternative polyadenylation revealed by targeted long read sequencing
Nature Communications|2023
36 cit.
7
Mesenchymal stem cells, as glioma exosomal immunosuppressive signal multipliers, enhance MDSCs immunosuppressive activity through the miR-21/SP1/DNMT1 positive feedback loop
Journal of Nanobiotechnology|2023
31 cit.
8
Chondrocyte fatty acid oxidation drives osteoarthritis via SOX9 degradation and epigenetic regulation
Nature Communications|2025
31 cit.
9
PTBP3 mediates TGF-β-induced EMT and metastasis of lung adenocarcinoma
Cell Cycle|2022
27 cit.
10
Bone marrow mesenchymal stem cell exosomes-derived microRNA-216a-5p on locomotor performance, neuronal injury, and microglia inflammation in spinal cord injury
Frontiers in Cell and Developmental Biology|2023
23 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Carlo M. Croce
The Ohio State University
2
Nikolaus Rajewsky
German Center for Neurodegenerative Diseases
3
Jan Lötvall
University of Gothenburg
4
Jørgen Kjems
Aarhus University
5
Muneesh Tewari
University of Michigan
6
David P. Bartel
Howard Hughes Medical Institute
7
Todd R. Golub
Broad Institute
8
Ke Zen
Nanjing Drum Tower Hospital
9
Li Yang
Fudan University
10
Burton B. Yang
Sunnybrook Health Science Centre

Papers

1
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
Nature Cell Biology|2007
12.8k cit.
2
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
Science|1999
11.6k cit.
3
MicroRNA expression profiles classify human cancers
Nature|2005
9.6k cit.
4
Most mammalian mRNAs are conserved targets of microRNAs
Genome Research|2008
8.6k cit.
5
Circular RNAs are a large class of animal RNAs with regulatory potency
Nature|2013
8.5k cit.
6
Natural RNA circles function as efficient microRNA sponges
Nature|2013
8.5k cit.
7
Circulating microRNAs as stable blood-based markers for cancer detection
Proceedings of the National Academy of Sciences|2008
8k cit.
8
Predicting effective microRNA target sites in mammalian mRNAs
eLife|2015
7.7k cit.
9
A microRNA expression signature of human solid tumors defines cancer gene targets
Proceedings of the National Academy of Sciences|2006
5.7k cit.
10
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
Science|2006
5.5k cit.

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