Leaderboards/Chromatin Remodeling and Cancer

Chromatin Remodeling and Cancer

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Matthew B. Maxwell
Salk Institute for Biological Studies
2
Leslie Duplaquet
Dana-Farber Brigham Cancer Center
3
Mario Iurlaro
Novartis (Switzerland)
4
Adam W. Turner
University of Virginia
5
Fernando J. de Miguel
Yale Cancer Center
6
Florencia Merino
Bernstein Center for Computational Neuroscience Munich
7
Yaniv Kazansky
Memorial Sloan Kettering Cancer Center
8
Jennifer Cantley
Arvinas (United States)
9
Sandipan Brahma
University of Nebraska Medical Center
10
Bennett Wolf
Harvard University

Papers

1
ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
Cell|2024
112 cit.
2
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
Cancer Cell|2024
46 cit.
3
Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF
Nature Genetics|2024
28 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Jingchun Zhu
University of California, Santa Cruz
2
Jeffrey M. Granja
Enable Biosciences (United States)
3
Aya Kobayashi
Wakayama Medical University
4
Diana C. Hargreaves
Salk Institute for Biological Studies
5
Mario Berríos
Hospital Universitario Central de Asturias
6
Lori Boice
Mayo Clinic
7
Tara Skelly
University of North Carolina at Chapel Hill
8
Vishal C. Chandan
University of California, Irvine
9
Tom Bodenheimer
University of North Carolina at Chapel Hill
10
Pei Lin
The University of Texas MD Anderson Cancer Center

Papers

1
ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
Cell|2024
112 cit.
2
Collaboration between distinct SWI/SNF chromatin remodeling complexes directs enhancer selection and activation of macrophage inflammatory genes
Immunity|2024
34 cit.
3
Light‐Controllable Binary Switch Activation of CAR T Cells
ChemMedChem|2022
15 cit.
4
Role of mRNA-binding proteins in retinal neovascularization
Experimental Eye Research|2024
6 cit.
5
Old macrophages lose their (circadian) rhythm
Trends in Immunology|2022
5 cit.
6
Coordination of transcription factors and SWI–SNF complexes regulates chromatin priming in developing T cells
Nature Immunology|2024
4 cit.
7
Transcription factor dependencies identify BAF-dependent cancers
Cancer Cell|2024
3 cit.
8
Switching under selection: how CoREST controls endocrine therapy resistance in ER+ breast cancer
Nature Structural & Molecular Biology|2022
1 cit.
9
RNA polymerase II promoter-proximal pausing promotes BAF chromatin binding and remodeling
Nature Genetics|2023
1 cit.
10
Abstract IA014: SWI/SNF complexes in development and disease
Cancer Research|2022
0 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Nada Jabado
McGill University
2
Charles W.M. Roberts
Harvard University
3
Jaclyn A. Biegel
Children's Hospital of Philadelphia
4
Gerald R. Crabtree
Stanford University
5
Olivier Delattre
Institut Curie
6
Robert E. Kingston
Harvard University
7
Cigall Kadoch
Broad Institute
8
Michael D. Taylor
Hospital for Sick Children
9
Kenneth W. Kinzler
Johns Hopkins University
10
Michael R. Stratton
Wellcome Sanger Institute

Papers

1
Signatures of mutational processes in human cancer
Nature|2013
10.1k cit.
2
An Integrated Genomic Analysis of Human Glioblastoma Multiforme
Science|2008
5.8k cit.
3
Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
Science|2008
4k cit.
4
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
Science|1997
3.9k cit.
5
Serial Analysis of Gene Expression
Science|1995
3.7k cit.
6
Identification of the breast cancer susceptibility gene BRCA2
Nature|1995
3.7k cit.
7
Patterns of somatic mutation in human cancer genomes
Nature|2007
3.1k cit.
8
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Nature|2012
2.7k cit.
9
Identification of FAP Locus Genes from Chromosome 5q21
Science|1991
2.4k cit.
10
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Nature|2016
2.3k cit.

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