Leaderboards/Cholesterol and Lipid Metabolism

Cholesterol and Lipid Metabolism

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Michael S. Haney
Neurosciences Institute
2
Dorian M. Cheff
Karolinska Institutet
3
Matheus B. Victor
Massachusetts Institute of Technology
4
Xiaoting Wu
Nanyang Technological University
5
Alexandra Litvinchuk
Hope Center for Neurological Disorders
6
Ju-Qiong Wang
Yonsei University
7
Daxin Cui
Sichuan University
8
Alex Reed
Scripps Research Institute
9
Juliane Tschuck
Helmholtz Zentrum München
10
Alberto Canfrán‐Duque
Yale University

Papers

1
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia
Nature|2024
474 cit.
2
Publication in Science Advances (2025) [55 citations, W4407160042]
Science Advances|2025
55 cit.
3
Identification of the Saga Complex As a Key Regulator of Hematopoiesis
Blood|2024
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Dirk Fitzner
Universitätsmedizin Göttingen
2
L. J. van Pelt
University Medical Center Groningen
3
Sumeet A. Khetarpal
Harvard University
4
Daniel B. Larach
Vanderbilt University Medical Center
5
Eunhye Choi
GeneMatrix (South Korea)
6
Trevor S. Tippetts
The University of Texas Southwestern Medical Center
7
Jinqi Liu
Shanghai University of Engineering Science
8
Wenlong Sun
Jiangnan University
9
Alena Grebe
University of Massachusetts Chan Medical School
10
Xu Qian
Zhejiang Cancer Hospital

Papers

1
Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma
Molecular Cell|2022
71 cit.
2
Naringenin Ameliorates Hyperuricemia by Regulating Renal Uric Acid Excretion via the PI3K/AKT Signaling Pathway and Renal Inflammation through the NF-κB Signaling Pathway
Journal of Agricultural and Food Chemistry|2022
64 cit.
3
Perioperative Opioids, the Opioid Crisis, and the Anesthesiologist
Anesthesiology|2022
58 cit.
4
Microbially produced vitamin B12 contributes to the lipid-lowering effect of silymarin
Nature Communications|2023
57 cit.
5
PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma
Cancer Research|2023
44 cit.
6
Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas
Nature Communications|2023
42 cit.
7
Polysaccharides Extracted from Old Stalks of <i>Asparagus officinalis</i> L. Improve Nonalcoholic Fatty Liver by Increasing the Gut Butyric Acid Content and Improving Gut Barrier Function
Journal of Agricultural and Food Chemistry|2025
36 cit.
8
Network pharmacology analysis to explore mechanism of Three Flower Tea against nonalcoholic fatty liver disease with experimental support using high-fat diet-induced rats
Chinese Herbal Medicines|2022
26 cit.
9
Reactivating PTEN to impair glioma stem cells by inhibiting cytosolic iron-sulfur assembly
Science Translational Medicine|2024
25 cit.
10
Beyond energy and growth: the role of metabolism in developmental signaling, cell behavior and diapause
Development|2023
22 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Michael S. Brown
Hospital of the University of Pennsylvania
2
Joseph L. Goldstein
Lasker Foundation
3
Alan R. Tall
Hanalei Watershed Hui
4
Peter Tontonoz
University of California, Los Angeles
5
David J. Mangelsdorf
Southwestern Medical Center
6
Helen H. Hobbs
Southwestern Medical Center
7
Hitoshi Shimano
University of Tsukuba
8
David W. Russell
Pfizer (United States)
9
Michael R. Hayden
University of British Columbia
10
Gerd Schmitz
University Hospital Regensburg

Papers

1
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
Journal of Clinical Investigation|2002
4k cit.
2
Prevalence of Hepatic Steatosis in An Urban Population in the United States: Impact of Ethnicity
Hepatology|2004
3.7k cit.
3
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
Cell|1994
3.5k cit.
4
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
Nature Genetics|2008
3.4k cit.
5
Sequence Variations in <i>PCSK9,</i> Low LDL, and Protection against Coronary Heart Disease
New England Journal of Medicine|2006
3.2k cit.
6
Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
Proceedings of the National Academy of Sciences|1979
2.5k cit.
7
mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.
Genes & Development|1994
2.2k cit.
8
Coated pits, coated vesicles, and receptor-mediated endocytosis
Nature|1979
2.1k cit.
9
ER Stress Induces Cleavage of Membrane-Bound ATF6 by the Same Proteases that Process SREBPs
Molecular Cell|2000
1.8k cit.
10
PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL
Cell|1998
1.8k cit.

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