Leaderboards/Chemotherapy-induced organ toxicity mitigation

Chemotherapy-induced organ toxicity mitigation

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Reem S. Alruhaimi
Princess Nourah bint Abdulrahman University
2
Letian Yang
China University of Petroleum, East China
3
Sandy R. Botros
Minia University
4
Medine Sibel Karağaç
Atatürk University
5
Dina A. AbdElrazek
Cairo University
6
Neslihan Öztürk
Atatürk University
7
Seenipandi Arunachalam
United Arab Emirates University
8
Paul O'Dowd
Royal College of Surgeons in Ireland
9
Fatemah A. Alherz
Princess Nourah bint Abdulrahman University
10
Waleed A.I. Khallaf
Beni-Suef University

Papers

1
Publication in Journal of Biochemical and Molecular Toxicology (2024) [50 citations, W4401403164]
Journal of Biochemical and Molecular Toxicology|2024
50 cit.
2
Unveiling the tyrosinase inhibitory potential of phenolics from Centaurium spicatum: Bridging in silico and in vitro perspectives
Bioorganic Chemistry|2024
43 cit.
3
Publication in Toxicology and Applied Pharmacology (2025) [19 citations, W4410176735]
Toxicology and Applied Pharmacology|2025
19 cit.
4
Integrating Computational Modeling and Experimental Validation to Unveil Tyrosinase Inhibition Mechanisms of Flavonoids from <i>Alhagi graecorum</i>
ACS Omega|2024
17 cit.
5
Ameliorative effects of rutin and rutin-loaded chitosan nanoparticles on testicular oxidative stress and histological damage induced by cyclophosphamide in male rats
Food and Chemical Toxicology|2024
16 cit.
6
Berberine attenuates inflammation and oxidative stress and modulates lymphocyte E‐NTPDase in acute hyperlipidemia
Drug Development Research|2024
13 cit.
7
Farnesol prevents chlorpyrifos nephrotoxicity by modulating inflammatory mediators, Nrf2 and FXR and attenuating oxidative stress
Food and Chemical Toxicology|2024
13 cit.
8
Functional Morphology of the Tongue and Laryngeal Entrance and Scanning Electron Microscopic Pattern of the Filter Feeding Apparatus of <i>Anas crecca</i>
Journal of Experimental Zoology Part A Ecological and Integrative Physiology|2024
13 cit.
9
Galangin attenuates chlorpyrifos-induced kidney injury by mitigating oxidative stress and inflammation and upregulating Nrf2 and farnesoid-X-receptor in rats
Environmental Toxicology and Pharmacology|2024
12 cit.
10
Structural adaptations of the beak and oropharyngeal cavity roof in migratory Anas crecca: Distinctive scanning electron microscopic pattern of its filter feeding apparatus
Zoologischer Anzeiger|2024
10 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Cüneyt Çağlayan
Bilecik Şeyh Edebali Üniversitesi
2
Xinxin Ci
Jilin University
3
Fares E.M. Ali
Al-Azhar University
4
Jaechan Leem
Daegu Catholic University
5
Sefa Küçükler
Atatürk University
6
Yanqing Song
Jilin University
7
Li Wang
Southwest Medical University
8
Basma G. Eid
King Abdulaziz University
9
Saima Shaheen
COMSATS University Islamabad
10
Iman Fatemi
Kerman University of Medical Sciences

Papers

1
Morin ameliorates methotrexate-induced hepatotoxicity via targeting Nrf2/HO-1 and Bax/Bcl2/Caspase-3 signaling pathways
Molecular Biology Reports|2023
73 cit.
2
Neuroprotective effects of 18β-glycyrrhetinic acid against bisphenol A-induced neurotoxicity in rats: involvement of neuronal apoptosis, endoplasmic reticulum stress and JAK1/STAT1 signaling pathway
Metabolic Brain Disease|2022
64 cit.
3
Daphnetin ameliorates PM2.5-induced airway inflammation by inhibiting NLRP3 inflammasome-mediated pyroptosis in CS-exposed mice
Biomedicine & Pharmacotherapy|2023
41 cit.
4
Protective effect of chrysin on indomethacin induced gastric ulcer in rats: role of multi-pathway regulation
Biotechnic & Histochemistry|2022
39 cit.
5
Piceatannol Affects Gastric Ulcers Induced by Indomethacin: Association of Antioxidant, Anti-Inflammatory, and Angiogenesis Mechanisms in Rats
Life|2022
36 cit.
6
Btg2 Promotes Focal Segmental Glomerulosclerosis via Smad3‐Dependent Podocyte‐Mesenchymal Transition
Advanced Science|2023
31 cit.
7
Apocynin abrogates methotrexate-induced nephrotoxicity: role of TLR4/NF-κB-p65/p38-MAPK, IL-6/STAT-3, PPAR-γ, and SIRT1/FOXO3 signaling pathways
Archives of Pharmacal Research|2023
29 cit.
8
Antioxidant, Antiapoptotic, and Anti-Inflammatory Effects of Hesperetin in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury
Molecules|2023
28 cit.
9
Hederagenin ameliorates cisplatin-induced acute kidney injury via inhibiting long non-coding RNA A330074k22Rik/Axin2/β-catenin signalling pathway
International Immunopharmacology|2022
27 cit.
10
Hesperidin counteracts chlorpyrifos-induced neurotoxicity by regulating oxidative stress, inflammation, and apoptosis in rats
Metabolic Brain Disease|2023
27 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Zheng Dong
Central South University
2
William Reeves
The University of Texas at San Antonio Health Science Center
3
E. Wiltshaw
Unknown
4
Sarwat Sultana
Jamia Hamdard
5
Dietrich Büsselberg
Weill Cornell Medical College in Qatar
6
José Pedraza‐Chaverrí
Universidad Nacional Autónoma de México
7
John P. Donohue
University of Nevada, Las Vegas
8
Joseph V. Bonventre
Brigham and Women's Hospital
9
Ayman M. Mahmoud
Manchester Metropolitan University
10
Alex Sparreboom
The Ohio State University

Papers

1
Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury
Kidney International|2002
1.9k cit.
2
Carboplatin dosage: prospective evaluation of a simple formula based on renal function.
Journal of Clinical Oncology|1989
1.9k cit.
3
Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects
Cancers|2011
1.8k cit.
4
<i>Cis</i>-Diamminedichloroplatinum, Vinblastine, and Bleomycin Combination Chemotherapy in Disseminated Testicular Cancer
Annals of Internal Medicine|1977
1.6k cit.
5
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
Nature Medicine|2010
1.3k cit.
6
Nephron organoids derived from human pluripotent stem cells model kidney development and injury
Nature Biotechnology|2015
933 cit.
7
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
Proceedings of the National Academy of Sciences|1997
880 cit.
8
Intrinsic Epithelial Cells Repair the Kidney after Injury
Cell stem cell|2008
867 cit.
9
Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2
Nature|1997
845 cit.
10
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
Nature Communications|2015
774 cit.

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