Leaderboards/Chemical synthesis and alkaloids

Chemical synthesis and alkaloids

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Maxemiliano V. Vargas
Multidisciplinary Association for Psychedelic Studies
2
Ling-Xiao Shao
Cornell University
3
Dongmei Cao
Center for Excellence in Molecular Cell Science
4
Natalie Hesselgrave
University of Maryland, Baltimore
5
Ling-Xiao Shao
Cornell University
6
Daniel Villiger
University of Zurich
7
Mkaddem Mounira Guedri
University of Gabès
8
Laura Ley
University Hospital of Basel
9
Ning‐Yi Wang
Jiangsu Normal University
10
Balázs Szigeti
Országos Korányi Tbc és Pulmonológiai Intézet

Papers

1
Assessing expectancy and suggestibility in a trial of escitalopram v. psilocybin for depression
Psychological Medicine|2024
73 cit.
2
Expectancy Effects in Psychedelic Trials
Biological Psychiatry Cognitive Neuroscience and Neuroimaging|2024
62 cit.
3
Advances in structure-based drug design: The potential for precision therapeutics in psychiatric disorders
Neuron|2024
26 cit.
4
Publication in Psychopharmacology (2025) [3 citations, W4408921376]
Psychopharmacology|2025
3 cit.
5
Theta-burst rTMS in schizophrenia to ameliorate negative and cognitive symptoms: a double-blind, sham-controlled, randomized clinical trial
European Psychiatry|2024
0 cit.
6
<i>R</i> -MDDMA is a Safer Analogue of MDMA with Therapeutic Potential
ACS Chemical Neuroscience|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Mendel Kaelen
Imperial College London
2
Lee E. Dunlap
Multidisciplinary Association for Psychedelic Studies
3
Chunyang Dong
Neurosciences Institute
4
Nusrat Jahan
Soonchunhyang University
5
Gül Dölen
Johns Hopkins University
6
E.A. Ramazanov
Sumgayit State University
7
Thilo Winzer
University of York
8
Yi Li
Wuhan No.1 Hospital
9
Jianjun Cheng
Anhui Normal University
10
Sheng Wang
Chinese Academy of Sciences

Papers

1
Psychedelics reopen the social reward learning critical period
Nature|2023
329 cit.
2
Structure-based discovery of nonhallucinogenic psychedelic analogs
Science|2022
305 cit.
3
Unlocking opioid neuropeptide dynamics with genetically encoded biosensors
Nature Neuroscience|2024
54 cit.
4
Flexible scaffold-based cheminformatics approach for polypharmacological drug design
Cell|2024
44 cit.
5
Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response
Journal of Medicinal Chemistry|2023
26 cit.
6
Advances in structure-based drug design: The potential for precision therapeutics in psychiatric disorders
Neuron|2024
26 cit.
7
Dual-acting antitumor agents targeting the A2A adenosine receptor and histone deacetylases: Design and synthesis of 4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine derivatives
European Journal of Medicinal Chemistry|2022
13 cit.
8
In Vivo and In Vitro Investigation of a Novel Gelatin/Sodium Polyacrylate Composite Hemostatic Sponge for Topical Bleeding
Journal of Functional Biomaterials|2023
13 cit.
9
Structural insights into constitutive activity of 5-HT <sub>6</sub> receptor
Proceedings of the National Academy of Sciences|2023
11 cit.
10
Design and Synthesis of Novel GPR139 Agonists with Therapeutic Effects in Mouse Models of Social Interaction and Cognitive Impairment
Journal of Medicinal Chemistry|2023
11 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Stephen L. Buchwald
Massachusetts Institute of Technology
2
Victor Snieckus
Queen's University
3
Gregory C. Fu
California Institute of Technology
4
Jon Clardy
Harvard University
5
Erick M. Carreira
Board of the Swiss Federal Institutes of Technology
6
Karl Anker Jørgensen
Aarhus University
7
Robin Carhart‐Harris
University of California, San Francisco
8
Neil K. Garg
University of California, Los Angeles
9
Phil S. Baran
Scripps Research Institute
10
Joan Bosch
Universitat de Barcelona

Papers

1
Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize
Angewandte Chemie International Edition|2012
3k cit.
2
Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands
Accounts of Chemical Research|2008
2.6k cit.
3
Catalysts for Suzuki−Miyaura Coupling Processes:  Scope and Studies of the Effect of Ligand Structure
Journal of the American Chemical Society|2005
1.8k cit.
4
Rational Development of Practical Catalysts for Aromatic Carbon−Nitrogen Bond Formation
Accounts of Chemical Research|1998
1.8k cit.
5
Versatile Catalysts for the Suzuki Cross-Coupling of Arylboronic Acids with Aryl and Vinyl Halides and Triflates under Mild Conditions
Journal of the American Chemical Society|2000
1.6k cit.
6
Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study
The Lancet Psychiatry|2016
1.5k cit.
7
Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole Alkaloids
European Journal of Organic Chemistry|2003
1.4k cit.
8
Trial of Psilocybin versus Escitalopram for Depression
New England Journal of Medicine|2021
1.4k cit.
9
Atomic Structures of the Human Immunophilin FKBP-12 Complexes with FK506 and Rapamycin
Journal of Molecular Biology|1993
1.2k cit.
10
Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin
Proceedings of the National Academy of Sciences|2012
1.2k cit.

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