Leaderboards/Cardiac Fibrosis and Remodeling

Cardiac Fibrosis and Remodeling

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Konrad Hoeft
RWTH Aachen University
2
Andrew L. Koenig
Washington University in St. Louis
3
Junedh Amrute
Amgen (United States)
4
Nicole R. Wong
Washington University in St. Louis
5
Man Rao
Second Affiliated Hospital of Zhejiang University
6
Claudio Humeres
Albert Einstein College of Medicine
7
Lingfang Zhuang
Shanghai Jiao Tong University
8
Jianfu Zhu
Sun Yat-sen University
9
Danrong Hu
Sichuan University
10
Nobuyuki Enzan
Kyushu University

Papers

1
Targeting immune–fibroblast cell communication in heart failure
Nature|2024
204 cit.
2
Fibroblast Smad7 Induction Protects the Remodeling Pressure-Overloaded Heart
Circulation Research|2024
34 cit.
3
ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts
Journal of Clinical Investigation|2024
19 cit.
4
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Science|2026
8 cit.
5
Publication in Journal of Cardiology (2025) [4 citations, W4410762861]
Journal of Cardiology|2025
4 cit.
6
Label-free single-cell RNA multiplexing leveraging genetic variability
Nature Communications|2024
3 cit.
7
Abstract 4140393: Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis
Circulation|2024
2 cit.
8
Abstract 151: Single Cell Transcriptional And Epigenetic Map Of Human Coronary Artery Disease In A Multi-ethnic Population
Arteriosclerosis Thrombosis and Vascular Biology|2024
0 cit.
9
Effects of Blood Cadmium Levels on Blood Pressure and the Risk of Hypertension in a Community-Based Elderly Population
Exposure and Health|2024
0 cit.
10
Abstract Or139: Single cell variant to enhancer to gene map for coronary artery disease
Arteriosclerosis Thrombosis and Vascular Biology|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Andrea Bredemeyer
Washington University in St. Louis
2
Xiaoxiang Yan
Shanghai Jiao Tong University
3
Maarten Hulsmans
Harvard University
4
Kun Yang
Zhejiang Lab
5
Jun Wan
Wuhan University
6
Chuanfu Li
East Tennessee State University
7
Marinos Kallikourdis
Humanitas University
8
Malina J. Ivey
University of Cincinnati Medical Center
9
Alexei Ilinykh
Australian Regenerative Medicine Institute
10
Paolo Kunderfranco
Humanitas University

Papers

1
Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction
Science Advances|2023
366 cit.
2
Recruited macrophages elicit atrial fibrillation
Science|2023
206 cit.
3
Lactate induces vascular permeability via disruption of VE-cadherin in endothelial cells during sepsis
Science Advances|2022
160 cit.
4
Orphan Nuclear Receptor NR4A3 Promotes Vascular Calcification via Histone Lactylation
Circulation Research|2024
89 cit.
5
MCC950, a Selective NLRP3 Inhibitor, Attenuates Adverse Cardiac Remodeling Following Heart Failure Through Improving the Cardiometabolic Dysfunction in Obese Mice
Frontiers in Cardiovascular Medicine|2022
47 cit.
6
Global Characteristics and Dynamics of Single Immune Cells After Myocardial Infarction
Journal of the American Heart Association|2022
46 cit.
7
Resolvin D1 Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Inflammation, Oxidative and Endoplasmic Reticulum Stress
Frontiers in Pharmacology|2022
29 cit.
8
Anti-Oxidative, Anti-Apoptotic, and M2 Polarized DSPC Liposome Nanoparticles for Selective Treatment of Atherosclerosis
International Journal of Nanomedicine|2023
29 cit.
9
RNA Helicase DDX5 Maintains Cardiac Function by Regulating <i>CamkIIδ</i> Alternative Splicing
Circulation|2024
23 cit.
10
Microglia‐Mediated Neuroimmune Response Regulates Cardiac Remodeling After Myocardial Infarction
Journal of the American Heart Association|2023
20 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Jeffery D. Molkentin
Cincinnati Children's Hospital Medical Center
2
Douglas L. Mann
Washington University in St. Louis
3
Eric N. Olson
Southwestern Medical Center
4
Nikolaos G. Frangogiannis
Albert Einstein College of Medicine
5
Francis G. Spinale
University of South Carolina
6
Kenneth R. Chien
Karolinska Institutet
7
Richard Lee
City of Hope
8
Matthias Nahrendorf
Massachusetts General Hospital
9
Merry L. Lindsey
Meharry Medical College
10
Michael Schneider
University of Teacher Education in Special Needs

Papers

1
A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy
Cell|1998
2.6k cit.
2
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
The Journal of Experimental Medicine|2007
2.3k cit.
3
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
Nature|2005
2.2k cit.
4
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
Proceedings of the National Academy of Sciences|2008
1.8k cit.
5
The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis
Developmental Cell|2008
1.8k cit.
6
Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
Proceedings of the National Academy of Sciences|2003
1.8k cit.
7
Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA
Science|2007
1.7k cit.
8
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure
Proceedings of the National Academy of Sciences|2006
1.5k cit.
9
Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation
Immunity|2014
1.4k cit.
10
Mammalian heart renewal by pre-existing cardiomyocytes
Nature|2012
1.3k cit.

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