Leaderboards/Alzheimer's disease research and treatments

Alzheimer's disease research and treatments

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
J Cummings
University of Nevada, Las Vegas
2
Alhamdu Adamu
Shanxi Medical University
3
Nicolas R Barthélemy
Washington University in St. Louis
4
Bruna Bellaver
University of Pittsburgh
5
Lynn van Olst
Northwestern University
6
Theophania Ashleigh
Cornell University
7
Wagner S. Brum
Universidade Federal do Rio Grande do Sul
8
Boyd Kenkhuis
Leiden University Medical Center
9
João Pedro Ferrari‐Souza
Universidade Federal do Rio Grande do Sul
10
Kun Leng
University of California, San Francisco

Papers

1
The role of neuroinflammation in neurodegenerative diseases: current understanding and future therapeutic targets
Frontiers in Aging Neuroscience|2024
427 cit.
2
Highly accurate blood test for Alzheimer’s disease is similar or superior to clinical cerebrospinal fluid tests
Nature Medicine|2024
408 cit.
3
Publication in Nature Medicine (2025) [103 citations, W4408201841]
Nature Medicine|2025
103 cit.
4
Publication in Molecular Neurodegeneration (2024) [39 citations, W4395110245]
Molecular Neurodegeneration|2024
39 cit.
5
A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings
Nature Communications|2024
30 cit.
6
Publication in Neurobiology of Aging (2024) [20 citations, W4390741856]
Neurobiology of Aging|2024
20 cit.
7
Publication in Nature Neuroscience (2025) [18 citations, W4415954575]
Nature Neuroscience|2025
18 cit.
8
mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes
Journal of Neuroinflammation|2024
14 cit.
9
Publication in Alzheimer s & Dementia (2025) [11 citations, W4410265736]
Alzheimer s & Dementia|2025
11 cit.
10
Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy
Neurology Genetics|2024
2 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Bianca M. Nfonoyim
Boston Children's Hospital
2
Victoria F. Beja-Glasser
Broad Institute
3
María Llorens‐Martín
Centro de Biología Molecular Severo Ochoa
4
Casey Lynch
Lighthouse Guild
5
Lin Jiang
China Agricultural University
6
Yakeel T. Quiroz
Harvard University
7
Miranda E. Orr
Washington University in St. Louis
8
Jin‐Tai Yu
Shanghai Medical College of Fudan University
9
Subashchandrabose Chinnathambi
National Institute of Mental Health and Neurosciences
10
Matthias E. Lauer
Roche (Switzerland)

Papers

1
Plasma proteomic profiles predict future dementia in healthy adults
Nature Aging|2024
259 cit.
2
Senolytic therapy in mild Alzheimer’s disease: a phase 1 feasibility trial
Nature Medicine|2023
247 cit.
3
Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man
Nature Medicine|2023
189 cit.
4
Plasma proteomic profiles predict individual future health risk
Nature Communications|2023
140 cit.
5
Identifying causal genes for depression via integration of the proteome and transcriptome from brain and blood
Molecular Psychiatry|2022
135 cit.
6
Sleep, physical activity, sedentary behavior, and risk of incident dementia: a prospective cohort study of 431,924 UK Biobank participants
Molecular Psychiatry|2022
111 cit.
7
Peripheral immunity is associated with the risk of incident dementia
Molecular Psychiatry|2022
110 cit.
8
Depression, Depression Treatments, and Risk of Incident Dementia: A Prospective Cohort Study of 354,313 Participants
Biological Psychiatry|2022
106 cit.
9
Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank
Nature Human Behaviour|2023
104 cit.
10
Plasma Glial Fibrillary Acidic Protein in the Alzheimer Disease Continuum: Relationship to Other Biomarkers, Differential Diagnosis, and Prediction of Clinical Progression
Clinical Chemistry|2023
97 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Dennis J. Selkoe
Brigham and Women's Hospital
2
Bradley T. Hyman
Harvard University
3
Virginia M.‐Y. Lee
Institute for Neurodegenerative Disorders
4
David M. Holtzman
Hope Center for Neurological Disorders
5
John Q. Trojanowski
University of Pennsylvania
6
Michel Goedert
MRC Laboratory of Molecular Biology
7
Oskar Hansson
Eli Lilly (United States)
8
Christopher M. Dobson
University of Cambridge
9
Rudolph E. Tanzi
Harvard University
10
Frank M. LaFerla
University of California, Irvine

Papers

1
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
Science|2006
6.6k cit.
2
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
The Lancet Neurology|2009
4.8k cit.
3
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
The Lancet Neurology|2013
4.4k cit.
4
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
Nature|2002
4.3k cit.
5
Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles
Neuron|2003
4.1k cit.
6
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Nature Medicine|2008
3.7k cit.
7
α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies
Proceedings of the National Academy of Sciences|1998
3.2k cit.
8
National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
Alzheimer s & Dementia|2012
3.2k cit.
9
National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach
Acta Neuropathologica|2011
2.9k cit.
10
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
Neurology|1992
2.7k cit.

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