Leaderboards/Alkaloids: synthesis and pharmacology

Alkaloids: synthesis and pharmacology

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Xiao‐Ju Si
Henan University of Technology
2
Zhi‐Han Chen
Jiangsu Normal University
3
Mkaddem Mounira Guedri
University of Gabès
4
Kaiqi Shang
Central South University
5
Steffen Breinlinger
Pharmac
6
Gema Casado‐Hidalgo
Universidad San Jorge
7
Eleanor Blair Towers
North Carolina State University
8
Rishab N. Iyer
Multidisciplinary Association for Psychedelic Studies
9
Hau Sun Sam Chan
University of Oxford
10
Rakshit S. Tanna
Washington State University Spokane

Papers

1
An Evaluation of Sex-Specific Pharmacokinetics and Bioavailability of Kokusaginine: An In Vitro and In Vivo Investigation
Pharmaceuticals|2024
68 cit.
2
Palladium-catalysed methylene C(sp3)–H lactamization and cycloamination enabled by chlorinated pyridine–pyridone ligands
Nature Synthesis|2024
22 cit.
3
Fast and green methodology based on miniaturised liquid–liquid extraction with a hydrophobic natural deep eutectic solvent of opium alkaloids from poppy seed beverages
Microchemical Journal|2024
7 cit.
4
Investigating the effect of different grinding conditions and methods on the concentration of opium alkaloids in poppy seeds as a good reduction practice
Journal of Food Composition and Analysis|2024
4 cit.
5
Publication in Biological Psychiatry Global Open Science (2024) [4 citations, W4401550078]
Biological Psychiatry Global Open Science|2024
4 cit.
6
Publication in MMWR Morbidity and Mortality Weekly Report (2026) [4 citations, W7140752204]
MMWR Morbidity and Mortality Weekly Report|2026
4 cit.
7
Boletus edulis as a healthy and prized edible mushroom: analysis of bioactive compounds and in vitro functional properties
Applied Food Research|2025
3 cit.
8
Publication in Translational Psychiatry (2024) [W4399038483]
Translational Psychiatry|2024
0 cit.
9
Publication in Drug and Alcohol Dependence (2024) [W4400574767]
Drug and Alcohol Dependence|2024
0 cit.
10
Publication in Drug Metabolism and Pharmacokinetics (2025) [W4410993592]
Drug Metabolism and Pharmacokinetics|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Yu‐Chen Zhang
Shenzhen University
2
Wei Tan
Yangtze University
3
Alison R. H. Narayan
University of Michigan
4
Thilo Winzer
University of York
5
Yi Li
Wuhan No.1 Hospital
6
Shao‐Hua Xiang
Southern University of Science and Technology
7
Chao‐Kuan Huang
Kaohsiung Medical University
8
Jiazhang Lian
Zhejiang University of Science and Technology
9
Takato Hiranita
The University of Texas at San Antonio Health Science Center
10
Shao‐Fei Ni
Shantou University

Papers

1
Biocatalytic oxidative cross-coupling reactions for biaryl bond formation
Nature|2022
182 cit.
2
Catalytic atroposelective synthesis
Nature Catalysis|2024
139 cit.
3
Progress in organocatalytic asymmetric (4+3) cycloadditions for the enantioselective construction of seven-membered rings
Science China Chemistry|2023
136 cit.
4
Biosynthesis of catharanthine in engineered Pichia pastoris
Nature Synthesis|2023
111 cit.
5
Synthetic Biology Toolkit for Marker-Less Integration of Multigene Pathways into <i>Pichia pastoris</i> via CRISPR/Cas9
ACS Synthetic Biology|2022
96 cit.
6
Construction of ajmalicine and sanguinarine de novo biosynthetic pathways using stable integration sites in yeast
Biotechnology and Bioengineering|2022
75 cit.
7
Enhancing Homologous Recombination Efficiency in <i>Pichia pastoris</i> for Multiplex Genome Integration Using Short Homology Arms
ACS Synthetic Biology|2022
63 cit.
8
Establishing <i>Komagataella phaffii</i> as a Cell Factory for Efficient Production of Sesquiterpenoid α-Santalene
Journal of Agricultural and Food Chemistry|2022
61 cit.
9
Retron-mediated multiplex genome editing and continuous evolution in <i>Escherichia coli</i>
Nucleic Acids Research|2023
51 cit.
10
Interactive Effects of µ-Opioid and Adrenergic-α2 Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine
Journal of Pharmacology and Experimental Therapeutics|2022
42 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Feng Shi
Northeastern University
2
James M. Cook
University of Wisconsin–Milwaukee
3
Xiao‐Dong Luo
Kunming Institute of Botany
4
Yasuyuki Kita
Ritsumeikan University
5
Dale L. Boger
Scripps Research Institute
6
Joan Bosch
Universitat de Barcelona
7
David W. C. MacMillan
Princeton University
8
Shu‐Li You
Shanghai Institute of Organic Chemistry
9
Sarah E. O’Connor
Max Planck Institute for Chemical Ecology
10
Phil S. Baran
Scripps Research Institute

Papers

1
Photoredox Catalysis in Organic Chemistry
The Journal of Organic Chemistry|2016
3.1k cit.
2
Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes
Science|2008
2.4k cit.
3
The advent and development of organocatalysis
Nature|2008
2.4k cit.
4
New Strategies for Organic Catalysis:  The First Highly Enantioselective Organocatalytic Diels−Alder Reaction
Journal of the American Chemical Society|2000
1.7k cit.
5
Merging photoredox with nickel catalysis: Coupling of α-carboxyl sp <sup>3</sup> -carbons with aryl halides
Science|2014
1.6k cit.
6
Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis
Nature|2011
1.3k cit.
7
Catalytic Asymmetric Dearomatization Reactions
Angewandte Chemie International Edition|2012
1.3k cit.
8
Synergistic catalysis: A powerful synthetic strategy for new reaction development
Chemical Science|2012
1.2k cit.
9
Discovery of an α-Amino C–H Arylation Reaction Using the Strategy of Accelerated Serendipity
Science|2011
1k cit.
10
Enantioselective α-Trifluoromethylation of Aldehydes via Photoredox Organocatalysis
Journal of the American Chemical Society|2009
973 cit.

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