Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2025The National Genomics Data Center (NGDC), which is a part of the China National Center for Bioinformation (CNCB), offers a comprehensive suite of database resources to support the global scientific community. Amidst the unprecedented accumulation of multi-omics data, CNCB-NGDC is committed to continually evolving and updating its core database resources through big data archiving, integrative analysis and value-added curation. Over the past year, CNCB-NGDC has expanded its collaborations with international databases and established new subcenters focusing on biodiversity, traditional Chinese medicine and tumor genetics. Substantial efforts have been made toward encompassing a broad spectrum of multi-omics data, developing innovative resources and enhancing existing resources. Notably, new resources have been developed for single-cell omics (scTWAS Atlas), genome and variation (VDGE), health and disease (CVD Atlas, CPMKG, Immunosenescence Inventory, HemAtlas, Cyclicpepedia, IDeAS), biodiversity and biosynthesis (RefMetaPlant, MASH-Ocean) and research tools (CCLHunter). All resources and services are publicly accessible at https://ngdc.cncb.ac.cn.
A highly selective chemiluminescent H2S sensorZhenyu Zhang, Huijing Jiang, Zhi Xing et al.|Sensors and Actuators B Chemical|2004 [Flow injection analysis of 3,4-dihydroxybenzoic acid with inhibited chemiluminescent detection].It was found that 3,4-dihydroxybenzoic acid (protocatechuric acid) inhibited chemiluminescence of luminol-H2O2 reaction catalyzed by Co2+. On this basis, a flow injection method has been developed for the determination of protocatechuric acid. The method is simple, convenient and sensitive with detection limit of 2.7 x 10(-7) mol/L and is effective to determine protocatechuric acid in the range of 1 x 10(-6)-1 x 10(-5) mol/L. The variation coefficient of eleven determinations for 8 x 10(-6) mol/L protocatechuric acid is 2.3%.
Small Modular Pressurized Water Reactors Combined With Conventional Thermal Power PlantSmall modular reactor is investigated worldwide with the advantages of lower initial investment and short construction period. Generally, the economy of small modular pressurized water reactor (PWR) is not as good as large PWR, so various applications of small PWR are investigated, such as marine reactor, heat supply and sea water desalination. Limited to the parameters of steam generator, the generating efficiency for the pressurized water reactor nuclear power plant is about 33%, while the steam temperature of supercritical fossil power plant can exceed 600°C and generating efficiency is more than 45%. The essence of a hybrid power plant is to use a fossil fuel to superheat wet steam in an outer steam superheating device, after the steam generator to improve the parameters of working fluid. On one hand, the innovative hybrid nuclear power plant which combines nuclear reactor with conventional thermal energy can improve the efficiency of small PWR. On the other hand, this hybrid power plant has lower carbon emission compared with traditional thermal power plant. This paper describes two different coupling schemes of small pressurized water reactor combined with supercritical thermal power plant using steam turbine. Efficiency of hybrid power plant is influenced by the coupling scheme, steam parameter of the superheating device outlet, the proportion of nuclear energy, efficiency of assemblies and so on. The plant efficiency becomes higher with the improvement of parameter of the superheating device’s outlet steam, and it is higher when the proportion of nuclear energy becomes lower. Take the 660MWt integrated small pressurized water reactor as an example, when the proportion of nuclear energy accounts for 48%, the thermal efficiency of this innovative hybrid power plant is about 43%,while the net efficiency is 41%, that is much higher than the efficiency of traditional pressurized water reactor, improving about 24 percent. As to the carbon emission, it depends on the coal consumption rate of power supply. The coal consumption rate of this hybrid power plant is 158g /kWh, while the consumption rate of thermal hybrid power plant is 280g/kWh, reducing about 44 percent. Also, the fundamental solutions of technical problems for this innovative hybrid power plant are discussed in the paper. Furthermore, several useful outcomes and suggestions for key equipments are put forward, such as the scheme of a superheating device and high-temperature steam turbine, and the possibility of using a lava boiler as the superheating device to improve the steam parameters after the steam generator is analyzed.
ICONE23-1913 DESIGN AND STUDY OF ENGINEERING TEST FACILITY : HELIUM CIRCULATORHuijing Jiang, Ping Ye, Gang Zhao et al.|The Proceedings of the International Conference on Nuclear Engineering (ICONE)|2015 Helium circulator is one of the key equipment of High-temperature Gas-cooled Reactor Pebble-bed Module (HTR-PM). In order to simulate most normal and accident operating conditions of helium circulator in HTR-PM, a full scale, rated flow rate and power, engineering test loop, which was called Engineering Test Facility - Helium Circulator (ETF-HC), was designed and established. Two prototypes of helium circulator, which was supported by Active Magnetic Bearing (AMB) or sealed by dry gas seals, would be tested on ETF-HC. Therefore, special interchangeable design was under consideration. ETF-HC was constructed compactly, which consisted of eleven sub-systems. In order to reduce the flow resistance of the circuit, special ducts, elbows, valves and flowmeters were selected. Two stages of heat exchange loops were designed and a helium - high pressure pure water heat exchanger was applied to ensure water wouldn't be vaporized while simulating accident conditions. Commissioning tests were carried out and operation results showed that ETF-HC meets the requirement of helium circulator operation. On this test facility, different kinds of experiments were supposed to be held, including mechanical and aerodynamic performance tests, durability tests and so on. These tests would provide the features and performance of helium circulator and verify its feasibility, availability and reliability.