Cited by 2.2kOpen Access
University of Washington
ORCID: 0000-0002-8901-1835Publishes on Genomics and Chromatin Dynamics, RNA and protein synthesis mechanisms, Single-cell and spatial transcriptomics. 64 papers and 17.9k citations.
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at the L2 larval stage, which provided >50-fold "shotgun" cellular coverage of its somatic cell composition. From these data, we defined consensus expression profiles for 27 cell types and recovered rare neuronal cell types corresponding to as few as one or two cells in the L2 worm. We integrated these profiles with whole-animal chromatin immunoprecipitation sequencing data to deconvolve the cell type-specific effects of transcription factors. The data generated by sci-RNA-seq constitute a powerful resource for nematode biology and foreshadow similar atlases for other organisms.