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Fangshuo Zheng

Chinese Academy of Sciences

Publishes on Neuroscience and Neuropharmacology Research, Epilepsy research and treatment, Mesenchymal stem cell research. 19 papers and 611 citations.

19Publications
611Total Citations

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Top publicationsby citations

GPR40 modulates epileptic seizure and NMDA receptor function
Yong Yang, Xin Tian, Demei Xu et al.|Science Advances|2018
Cited by 65Open Access

-methyl-d-aspartate (NMDA) receptor-mediated synaptic transmission. Moreover, GPR40 regulated NR2A and NR2B expression on the surface of neurons. In addition, endocytosis of NMDA receptors and binding of GPR40 with NR2A and NR2B can be regulated by GPR40. Together, our findings indicate that GPR40 modulates epileptic seizures, providing a novel antiepileptic target.