Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 InhibitorsMichael A. Brodney, Brian T. O’Neill, Kevin E. Henegar et al.|Journal of Medicinal Chemistry|2015Cited by 78
Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug DesignChristopher R. Butler, Brian T. O’Neill, Michael A. Brodney et al.|Journal of Medicinal Chemistry|2015Cited by 46
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking HypopigmentationBrian T. O’Neill, Michael A. Brodney, Elizabeth M. Beck et al.|Journal of Medicinal Chemistry|2018Cited by 42
Utilizing CYP2D6 and BACE1 Structure Complexes to Reduce Risk of Drug-Drug Interactions with a Novel Series of Centrally Efficacious BACE1 InhibitorsMichael A. Brodney, Brian T. O’Neill, Elizabeth M. Beck et al.|Unknown|2015Cited by 1
CCDC 1829109: Experimental Crystal Structure DeterminationBrian T. O’Neill, Michael A. Brodney, Elizabeth M. Beck et al.|The Cambridge Structural Database|2018Cited by 0