Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loopThomas Eicher, Klaas M. Pos, Jürgen A. Bohnert et al.|Proceedings of the National Academy of Sciences|2012Cited by 343
Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrBThomas Eicher, Klaas M. Pos, Kay Diederichs et al.|eLife|2014Cited by 179
Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrBMarkus A. Seeger, Klaas M. Pos, Christoph von Ballmoos et al.|Nature Structural & Molecular Biology|2008Cited by 152
The AcrB Efflux Pump: Conformational Cycling and Peristalsis Lead to Multidrug ResistanceMarkus A. Seeger, Klaas M. Pos, Kay Diederichs et al.|Current Drug Targets|2008Cited by 121