Columbia University Irving Medical Center
ORCID: 0000-0003-2459-909XPublishes on Video Coding and Compression Technologies, Advanced Data Compression Techniques, Cancer Genomics and Diagnostics. 165 papers and 12.7k citations.
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Models and results are presented that assess the performance of statistical multiplexing of independent video sources. Presented results indicate that the probability of buffering (or delaying) video data beyond an acceptable limit drops dramatically as the number of multiplexed sources increases beyond one. This demonstrates that statistical or asynchronous time-division multiplexing (TDM) can efficiently absorb temporal variations of the bit rate of individual sources without the significant variations in reception quality exhibited by multimode videocoders for synchronous TDM or circuit-switched transmission. Two source models are presented. The first model is an autoregressive continuous-state, discrete-time Markov process, which was used to generate source data in simulation experiments. The second model is a discrete-state, continuous-time Markov process that was used in deriving a fluid-flow queuing analysis. The presented study shows that both models generated consistent numerical results in terms of queuing performance.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Genomics is a highly cross-disciplinary field that creates paradigm shifts in such diverse areas as medicine and agriculture. It is believed that many significant scientific and technological endeavors in the 21st century will be related to the processing and interpretation of the vast information that is currently revealed from sequencing the genomes of many living organisms, including humans. Genomic information is digital in a very real sense; it is represented in the form of sequences of which each element can be one out of a finite number of entities. Such sequences, like DNA and proteins, have been mathematically represented by character strings, in which each character is a letter of an alphabet. In the case of DNA, the alphabet is size 4 and consists of the letters A, T, C and G; in the case of proteins, the size of the corresponding alphabet is 20. As the list of references shows, biomolecular sequence analysis has already been a major research topic among computer scientists, physicists, and mathematicians. The main reason that the field of signal processing does not yet have significant impact in the field is because it deals with numerical sequences rather than character strings. However, if we properly map a character string into, one or more numerical sequences, then digital signal processing (DSP) provides a set of novel and useful tools for solving highly relevant problems. For example, in the form of local texture, color spectrograms visually provide significant information about biomolecular sequences which facilitates understanding of local nature, structure, and function. Furthermore, both the magnitude and the phase of properly defined Fourier transforms can be used to predict important features like the location and certain properties of protein coding regions in DNA. Even the process of mapping DNA into proteins and the interdependence of the two kinds of sequences can be analyzed using simulations based on digital filtering. These and other DSP-based approaches result in alternative mathematical formulations and may provide improved computational techniques for the solution of useful problems in genomic information science and technology.
In this paper, we present a nonlinear interpolation scheme for still image resolution enhancement. The algorithm is based on a source model emphasizing the visual integrity of detected edges and incorporates a novel edge fitting operator that has been developed for this application. A small neighborhood about each pixel in the low-resolution image is first mapped to a best-fit continuous space step edge. The bilevel approximation serves as a local template on which the higher resolution sampling grid can then be superimposed (where disputed values in regions of local window overlap are averaged to smooth errors). The result is an image of increased resolution with noticeably sharper edges and, in all tried cases, lower mean-squared reconstruction error than that produced by linear techniques.