IMGT(R), the international ImMunoGeneTics information system(R)IMGT, the international ImMunoGeneTics information system (http://www.imgt.org), was created in 1989 by Marie-Paule Lefranc, Laboratoire d'ImmunoGénétique Moléculaire LIGM (Université Montpellier 2 and CNRS) at Montpellier, France, in order to standardize and manage the complexity of immunogenetics data. The building of a unique ontology, IMGT-ONTOLOGY, has made IMGT the global reference in immunogenetics and immunoinformatics. IMGT is a high-quality integrated knowledge resource specialized in the immunoglobulins or antibodies, T cell receptors, major histocompatibility complex, of human and other vertebrate species, proteins of the IgSF and MhcSF, and related proteins of the immune systems of any species. IMGT provides a common access to standardized data from genome, proteome, genetics and 3D structures. IMGT consists of five databases (IMGT/LIGM-DB, IMGT/GENE-DB, IMGT/3Dstructure-DB, etc.), fifteen interactive online tools for sequence, genome and 3D structure analysis, and more than 10,000 HTML pages of synthesis and knowledge. IMGT is used in medical research (autoimmune diseases, infectious diseases, AIDS, leukemias, lymphomas and myelomas), veterinary research, biotechnology related to antibody engineering (phage displays, combinatorial libraries, chimeric, humanized and human antibodies), diagnostics (clonalities, detection and follow-up of residual diseases) and therapeutical approaches (graft, immunotherapy, vaccinology). IMGT is freely available at http://www.imgt.org.
Phosphate Ester‐Modified Acceptor Additives Enable Concurrent Vertical Morphology and Interfacial Engineering for Organic Solar Cells Approaching 21% EfficiencyJiahao Zhang, Yu Chen, Weilin Zhou et al.|Advanced Materials|2026 Organic solar cells (OSCs) based on non-fullerene acceptors (NFAs) have progressed rapidly, yet further gains are constrained by coupled challenges in vertical morphology control and energy alignment at the acceptor-cathode interface. Here, a molecular engineering strategy is presented that installs strongly polar phosphate ester groups onto the inner alkyl chains of the benchmark NFA L8-BO, yielding two derivatives-1POE and 2POE. Employed as non-volatile solid additives during layer-by-layer processing, these molecules induce vertical composition redistribution to form a graded donor-acceptor-additive architecture. The resulting vertical profiling strengthens intermolecular interactions, raises surface energy, and drives additive accumulation near the top interface, thereby improving interfacial energetics and facilitating electron extraction. Consequently, devices incorporating 2 wt.% 1POE or 2POE deliver power conversion efficiencies (PCEs) of 19.87% and 19.28%, respectively, versus 18.83% for controls, alongside enhanced operational stability. The strategy shows strong universality across multiple blends, achieving a PCE of 20.90% in a D18/L8-BO:BTP-eC9FCl ternary system. These results demonstrate that precise phosphate ester-based additive design enables concurrent optimization of vertical phase distribution and interfacial energetics, offering a practical route to high-efficiency, stable OSCs.
Molecular Integration Strategy Enables Simultaneous Modulation of Crystal Growth and Interfacial Energy Loss for Efficient Inverted Perovskite Solar CellsYuqi Yao, Qi Wang, Wei Hui et al.|Angewandte Chemie|2025 Abstract Severe interfacial energy loss and inferior crystal quality remain key limitations for high‐performance perovskite solar cells (PSCs). Herein, we report a multifunctional molecule, 1,3‐propanediamine dimercaptoacetate (PDA(AcSH) 2 ), designed through a molecular‐integration strategy to address these challenges simultaneously. The PDA 2+ cations preferentially accumulate at the perovskite/C 60 interface, establishing a field‐effect passivation that suppresses interfacial contact induced non‐radiative recombination. Meanwhile, the AcSH – anions are homogeneously distributed throughout the perovskite layer, mediating crystal growth and passivating charged traps via dual binding of ─SH and ─COO – groups. The reducible ─SH groups in AcSH – also convert photo‐thermally generated I 2 /I 3 – species into I – , forming reversible S─S dimers that photodecompose under UV light illumination to regenerate ─SH groups. This enables a self‐sustaining redox cycle for dynamic defect healing and enhances both precursor and film stability. Consequently, the optimized small‐area (0.09‐cm 2 ) device achieves impressive efficiency of 26.88% and a non‐radiative voltage loss of only 64 mV. The strategy is readily scalable, delivering efficiencies of 24.92% and 22.73% for 1‐cm 2 device and 12.96‐cm 2 mini‐module, respectively. This work highlights the effectiveness of rational molecular design in mitigating both bulk and interfacial energy losses, paving the way for the next generation of high‐performance, stable, and scalable PSCs.